ArticleAnnals of clinical and translational neurology2026
Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre-Existing Renal Impairment.
Article in Annals of clinical and translational neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesAcute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre-existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high-risk population.
methodsThis retrospective, two-center study involved 310 patients who underwent MT for ischemic stroke and presented with impaired renal function at baseline (eGFR < 60 mL/min/1.73 m
resultsAcute kidney injury occurred in 91 patients, including 49 with PC-AKI and 42 with L-AKI. Patients who developed AKI were more likely to have pre-existing chronic kidney disease, prior NSAIDs use, and higher serum glucose and potassium levels at admission. Additionally, AKI was associated with longer hospitalization, increased in-hospital and 3-month mortality, and less favorable clinical outcomes overall. The independent predictors of AKI included NIHSS > 15 (OR: 3.441), WBC count (OR: 1.128), female sex (OR: 0.311), and the comorbidity burden (OR: 2.414).
interpretationAcute kidney injury represents a frequent and clinically relevant complication following MT in patients with pre-existing renal impairment. Early recognition and the implementation of preventive strategies are essential, particularly in patients with established risk factors for AKI.
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