Evidence map›Paper›PMID 42417610›Full record

ArticleeLife2026

Cribriform plate microenvironment assembles a suppressive myeloid network during EAE-induced neuroinflammation.

Collin Laaker, Martin Hsu, Andy Madrid, Jenna Port, Sophia M Vrba, Melinda Herbath, Cameron Baenen, Mohan Kumar, Thanthrige Thiunuwan Priyathilaka, Matyas Sandor and 1 more

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Collin LaakerNeuroscience Training Program, University of Wisconsin Madison, Madison, United States.ORCID 0000-0001-8532-9427
Martin HsuDepartment of Microbiology-Immunology, University of North Carolina, Chapel Hill, United States.
Andy MadridNeuroscience Training Program, University of Wisconsin Madison, Madison, United States.
Jenna PortDepartment of Pathology and Laboratory Medicine, School of Medicine and Public Health, University of Wisconsin Madison, Madison, United States.ORCID 0000-0001-5968-7626
Sophia M VrbaDepartment of Pathology and Laboratory Medicine, School of Medicine and Public Health, University of Wisconsin Madison, Madison, United States.ORCID 0000-0003-1679-8240
Melinda HerbathDepartment of Pathology and Laboratory Medicine, School of Medicine and Public Health, University of Wisconsin Madison, Madison, United States.ORCID 0000-0002-8403-582X
Cameron BaenenDepartment of Pathology and Laboratory Medicine, School of Medicine and Public Health, University of Wisconsin Madison, Madison, United States.
Mohan KumarDepartment of Pathology and Laboratory Medicine, School of Medicine and Public Health, University of Wisconsin Madison, Madison, United States.
Thanthrige Thiunuwan PriyathilakaDepartment of Pathology and Laboratory Medicine, School of Medicine and Public Health, University of Wisconsin Madison, Madison, United States.
Matyas Sandor *Department of Pathology and Laboratory Medicine, School of Medicine and Public Health, University of Wisconsin Madison, Madison, United States.ORCID 0000-0001-6463-6807
Zsuzsanna Fabry *Department of Pathology and Laboratory Medicine, School of Medicine and Public Health, University of Wisconsin Madison, Madison, United States.ORCID 0000-0003-4555-9732

Funding

Integrated Training For Physician-ScientistsT32GM140935 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Anna Huttenlocher, Jeniel E Nett · 2021 to 2026
$6.5M
Neuroscience Training ProgramT32NS105602 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI Ari Rosenberg · 2019 to 2026
$2.5M
Graduate Training in Cellular and Molecular Pathogenesis of Human DiseasesT32GM135119 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Zsuzsanna Fabry · 2020 to 2026
$2.2M
American Heart Association 915125NIGMS NIH HHS T32GM135119NIGMS NIH HHS T32GM140935NINDS NIH HHS NS123449NINDS NIH HHS NS126595NINDS NIH HHS T32NS105602
6 · The paper itself

Abstract

During neuroinflammation, CD11c

Indexed as

Cellular MicroenvironmentEncephalomyelitis, Autoimmune, ExperimentalMyeloid CellsNeuroinflammatory DiseasesAnimalsDendritic CellsDisease Models, AnimalFemaleMacrophagesMeningesMiceMice, Inbred C57BLcribriform plateimmunologyinflammationmouseneuroimmunologyneuroscience

Identifiers

PMID42417610
PMCPMC13345627

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.