Effects of Different Dietary Inclusion Levels of Soybean Meal Supplemented with Crystalline Amino Acids on Mineral Deposition in Different Tissues of Weaned Piglets.

Luqi Cai, Ting Yao, Liuqin He, Yulong Yin, Tiejun Li

Abstract read

In one paragraph

Article in Biological trace element research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luqi Cai *Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process, CAS Key Laboratory of Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, 410125, China.

Ting Yao *Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process, CAS Key Laboratory of Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, 410125, China.

Liuqin HeHunan Provincial Key Laboratory of Animal Intestinal Function and Regulation, Laboratory of Animal Nutrition and Human Health, College of Life Sciences, Hunan Normal University, Changsha, 410081, China. heliuqin@hunnu.edu.cn.

Yulong YinHunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process, CAS Key Laboratory of Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, 410125, China.

Tiejun LiHunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process, CAS Key Laboratory of Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, 410125, China. tjli@isa.ac.cn.

Funding

Key Fundamental Research Program of Hunan Province 2024JC0007National Natural Science Foundation of China U23A20233special Project for High-Tech Industrialization via Science and Technology Cooperation between Jilin Province and the Chinese Academy of Sciences 2026SYH1Z0017the Academician Special Project of Xinjiang Silk Road 542 Science and Technology Development Program (2024LQ02007)

6 · The paper itself

Abstract

This study investigated the effects of reducing soybean meal (SBM) with balanced essential amino acids (EAAs) and supplementing non-essential amino acids (NEAAs) on organ development and mineral deposition in weaned piglets. In Experiment 1, forty-nine 28-day-old piglets (Duroc × Landrace × Large White) were randomly assigned to seven groups (n = 7) and fed corn-soybean meal diets with varying SBM inclusion levels (30% to 0%) with balanced EAAs (Lys, Met, Thr, Trp, Val, Ile, Leu, Arg, His, and Phe). In Experiment 2, twenty-eight piglets were allocated to four groups (n = 7) and fed SBM-free diets balanced for EAAs and supplemented with high, medium, or low levels of NEAAs. The results showed that reducing SBM balanced with EAAs did not impair growth performance while significantly altered mineral deposition. Calcium (Ca) concentrations in the heart, liver, and carcass, alongside carcass phosphorus (P) and serum zinc (Zn) were declined linearly. Conversely, liver Zn, kidney P, serum alanine aminotransferase (ALT) activities and and alkaline phosphatase (ALP) were increased. Serum iron (Fe) and albumin levels were exhibited U-shaped trends, reaching their nadir at moderate SBM levels. Moreover, based on the above diet, balancing NEAA significantly enhanced mineral deposition, and partially ameliorated hepatic stress indicators. These results suggest that although SBM reduction maintains growth, it disrupts mineral deposition and organ health. Our findings provide a strategy that supplementing with high dosage NEAAs in EAA-balanced low-protein diets is recommended to maintain mineral homeostasis.

Indexed as

Amino AcidsDietary SupplementsGlycine maxMineralsAnimal FeedAnimalsLiverSwineWeaningAmino AcidsMineralsAmino acidsLow-protein dietMineral depositionWeaned piglets

Identifiers

PMID42418128

DOI10.1016/0305-0491(95)02138-8

What Socratic holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.