Evidence map›Paper›PMID 42419821›Full record

ArticleBMJ open respiratory research2026

Retrospective analysis of acute admissions for interstitial lung disease suggests a complex, multifactorial association between social deprivation and 90-day all-cause mortality: data from the North West of England.

Laura J White, Jonathon Shaw, Bethan Powell, Nyan M Kyi, Alicia Sou, Gareth Edward Hughes, Dilanka Tilakaratne, Conal Hayton, Trishala Raj, Vi Truong and 16 more

Abstract readMulticenter Study
In one paragraph

Article in BMJ open respiratory research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Laura J WhiteLancaster Medical School, Lancaster University, Lancaster, England, UK l.j.white@lancaster.ac.uk.ORCID http://orcid.org/0009-0003-1991-3897
Jonathon ShawDepartment of Respiratory Medicine, Stockport NHS Foundation Trust, Stockport, UK.
Bethan PowellDepartment of Respiratory Medicine, Blackpool Teaching Hospitals NHS Foundation Trust, Blackpool, UK.
Nyan M KyiDepartment of Respiratory Medicine, Northern Care Alliance NHS Foundation Trust, Salford, England, UK.
Alicia SouDepartment of Respiratory Medicine, Northern Care Alliance NHS Foundation Trust, Salford, England, UK.
Gareth Edward HughesDepartment of Respiratory Medicine, Bolton NHS Foundation Trust, Bolton, UK.ORCID http://orcid.org/0000-0003-2942-6489
Dilanka TilakaratneDepartment of Respiratory Medicine, Bolton NHS Foundation Trust, Bolton, UK.
Conal HaytonDepartment of Respiratory Medicine, Manchester University NHS Foundation Trust, Manchester, England, UK.
Trishala RajDepartment of Respiratory Medicine, Manchester University NHS Foundation Trust, Manchester, England, UK.
Vi TruongDepartment of Respiratory Medicine, Manchester University NHS Foundation Trust, Manchester, England, UK.
Nashwah IsmailDepartment of Respiratory Medicine, Manchester University NHS Foundation Trust, Manchester, England, UK.
Nawat KhanijounDepartment of Respiratory Medicine, Manchester University NHS Foundation Trust, Manchester, England, UK.
Rebecca HuangDepartment of Respiratory Medicine, Tameside and Glossop Integrated Care NHS Foundation Trust, Ashton-under-Lyne, England, UK.
Emma HardyDepartment of Respiratory Medicine, Tameside and Glossop Integrated Care NHS Foundation Trust, Ashton-under-Lyne, England, UK.
Mahzaib BabarDepartment of Respiratory Medicine, Tameside and Glossop Integrated Care NHS Foundation Trust, Ashton-under-Lyne, England, UK.
Naayaab KhanDepartment of Respiratory Medicine, Tameside and Glossop Integrated Care NHS Foundation Trust, Ashton-under-Lyne, England, UK.
Martin ReganDepartment of Respiratory Medicine, Tameside and Glossop Integrated Care NHS Foundation Trust, Ashton-under-Lyne, England, UK.
Oby OkpalaDepartment of Respiratory Medicine, Tameside and Glossop Integrated Care NHS Foundation Trust, Ashton-under-Lyne, England, UK.
Ragavilasini SureshDepartment of Respiratory Medicine, Tameside and Glossop Integrated Care NHS Foundation Trust, Ashton-under-Lyne, England, UK.
Jerome McintoshDepartment of Respiratory Medicine, Tameside and Glossop Integrated Care NHS Foundation Trust, Ashton-under-Lyne, England, UK.
Amsal AmjadDepartment of Respiratory Medicine, Tameside and Glossop Integrated Care NHS Foundation Trust, Ashton-under-Lyne, England, UK.
Mahum SohailDepartment of Respiratory Medicine, Tameside and Glossop Integrated Care NHS Foundation Trust, Ashton-under-Lyne, England, UK.
Zainab AslamDepartment of Respiratory Medicine, Tameside and Glossop Integrated Care NHS Foundation Trust, Ashton-under-Lyne, England, UK.
Amy GadoudLancaster Medical School, Lancaster University, Lancaster, England, UK.
Timothy GatheralLancaster Medical School, Lancaster University, Lancaster, England, UK.
Georges Ng Man KwongDepartment of Respiratory Medicine, Northern Care Alliance NHS Foundation Trust, Salford, England, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSocial deprivation impacts chronic disease and acute admission outcomes. In interstitial lung disease (ILD), prior British Thoracic Society registry data for idiopathic pulmonary fibrosis have shown high deprivation was associated with poorer long-term outcomes. However, its impact on acute admissions in ILD is not known.

methodsWe undertook a multicentre, retrospective study of ILD-related admissions between 1 January 2017 and 31 December 2019 across 11 hospitals in the North West of England, using available real-world data. We determined social deprivation geographically by the 2019 English Indices of Deprivation deciles. The primary outcome was 90-day all-cause mortality.

results999 admissions met the inclusion criteria. 327/999 (32.7%) of admissions came from individuals geographically in the most deprived 20%. Across 999 admissions, in unadjusted survival analysis, we observed a non-linear relationship between deprivation and 90-day all-cause mortality. In complete case multivariate modelling, deprivation demonstrated borderline significant association with all-cause mortality (HR 1.038, 95% CI 1.00 to 1.077, p=0.050). However, this effect was lost in pooled analysis using multiple imputation (HR 1.001, 95% CI 0.971 to 1.033, p=0.924). Male sex and pre-admission long-term oxygen were consistently associated with increased 90-day all-cause mortality across both models. Lower transfer factor for carbon monoxide values were significantly associated with increased 90-day mortality in pooled analysis.

conclusionWe observe a high burden of acute ILD-related hospital admission among the most deprived 20%, suggesting geographical deprivation may impact acute healthcare seeking behaviours. Once admitted, the impact of deprivation appears more complex and multifactorial. Further studies which assess geographical and individual-level deprivation are needed to validate our findings.

Indexed as

HospitalizationLung Diseases, InterstitialPatient AdmissionSocial DeprivationAgedAged, 80 and overEnglandFemaleHumansMaleMiddle AgedRetrospective StudiesSocioeconomic Disparities in HealthClinical EpidemiologyIdiopathic Pulmonary FibrosisInterstitial FibrosisPatient Outcome Assessment

Identifiers

PMID42419821
PMCPMC13347911

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.