Evidence mapPaperPMID 42419872Full record

Trial reportOpen heart2026

Prognostic value of baseline and longitudinal changes in exercise capacity and quality of life in the HF-Wii Swedish population.

Joanna-Maria Papageorgiou, Tiny Jaarsma, Kristofer Hedman, Nadine Karlsson, Leonie Verheijden Klompstra, Anna Strömberg

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Open heart, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01785121 (Increasing Exercise Capacity of Patients With Heart Failure by Wii Gaming), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01785121 nacompletednot on this map

Increasing Exercise Capacity of Patients With Heart Failure by Wii Gaming (HF-Wii) A Randomized Controlled Trial

TypeinterventionalSponsorLinkoeping UniversityRan2013 to 2018Enrolled605ConditionsHeart FailureArmsStructured access to a Wii game computer (Wii), Motivational support only
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joanna-Maria PapageorgiouDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden joanna-maria.papageorgiou@liu.se.ORCID http://orcid.org/0000-0002-9849-6897
Tiny JaarsmaDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
Kristofer HedmanDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.ORCID http://orcid.org/0000-0002-3751-7180
Nadine KarlssonDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.ORCID http://orcid.org/0000-0003-0279-5903
Leonie Verheijden KlompstraDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
Anna StrömbergDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to explore whether baseline values and 12-month change in the 6-Minute Walk Distance (6MWD) and the physical scale of the Minnesota Living with Heart Failure Questionnaire (MLHFQ) were associated with long-term mortality in patients with heart failure (HF).

methodsA total of 333 patients with HF, enrolled in the HF-Wii trial (NCT01785121) in Sweden, were included. Data on long-term mortality were gathered 3 years after study completion of the last patient included. Study participants were stratified into three groups based on baseline results of the 6MWD: group 1: ≤383 m, group 2: 384-450 m and group 3: ≥451 m. Similarly, tertiles were formed according to baseline MLHFQ physical domain scores: group 1: 0-5 points, group 2: 6-12 points and group 3: 13-40 points.

resultsDuring a median (25th-75th percentiles) follow-up of 1900 (1566, 2271) days, 48 patients died (14.4%). Patients in group 1 of 6MWD displayed a more severe clinical status in comparison to patients in groups 2 and 3. Kaplan-Meier survival analysis showed a statistically significant between-group difference in survival, observed per tertile groups of the baseline 6MWD. However, no significant difference in survival was found in relation to changes in 6MWD over time. Likewise, there were not statistically significant between-group differences in survival per tertile groups of the baseline score on the physical domain of MLHFQ nor with respect to change over time of the same score.

conclusionsBaseline 6MWD demonstrated significant prognostic value for long-term mortality in patients with HF whereas the physical score of MLHFQ, as well as their 12-month changes did not reach statistical significance. TRIAL REGISTRATION NUMBER: NCT01785121.

Indexed as

Exercise ToleranceHeart FailureQuality of LifeAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisSurveys and QuestionnairesSurvival RateSwedenTime FactorsWalk TestCardiac RehabilitationHEART FAILUREOutcome Assessment, Health Care

Identifiers

PMID42419872
PMCPMC13347824

What Socratic holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.