ArticleCardiovascular and interventional radiology2026
Predictive Value of Baseline High-Resolution MRI Features for In-Stent Restenosis in Symptomatic Nonacute Intracranial Atherosclerotic Occlusion.
Article in Cardiovascular and interventional radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Seeing Intracranial in-Stent Restenosis Before it Happens: What Baseline Vessel Wall Imaging Can-and Can't-Tell Us Yet.Cardiovascular and interventional radiology · 2026Article
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Authors and funding
9 authors.
Funding
Abstract
purposeAmong symptomatic nonacute intracranial atherosclerotic occlusion (ICAO), endovascular recanalization has shown potential efficacy and acceptable periprocedural complications. However, the long-term benefits of stent implantation could be diminished by in-stent restenosis (ISR). This study aimed to investigate the association between radiological features on preoperative high-resolution MRI (HR-MRI) and ISR. MATERIALS AND
methodsWe retrospectively reviewed 103 patients with symptomatic nonacute ICAO who underwent stenting between January 2018 to December 2024 at our institution. Patients' clinical-hematological parameters, HR-MRI features and procedural results were collected. Potential factors related to ISR were analyzed by univariate and multivariate analyses.
resultsAt a median 4.1-month imaging follow-up, this study observed a ISR rate of 29.1% (30/103) after stenting for nonacute ICAO. Based on multivariate analysis, plaque enhancement amplitude (≥ 1.43 vs. < 1.43, OR 3.960 (95% CI 1.279-12.265); P = 0.017), lumen collapsibility index (≥ 29.3% vs. < 29.3%, OR 5.124 (95% CI 1.703-15.413); P = 0.004), and degree of residual stenosis after recanalization (≥ 20.6% vs. < 20.6%, OR 5.311 (95% CI 1.832-15.400); P = 0.002) were independent ISR predictors. Furthermore, from 0 to 3 of these risk factors, the incidence of ISR increased significantly (6.5%, 17.1%, 61.9%, and 80.0%, respectively; P < 0.001).
conclusionsIn symptomatic nonacute ICAO patients, the baseline HR-MRI features were identified valuable for predicting ISR and individualized intervention of these imaging features may be beneficial to reduce restenosis risk. Further research with larger sample sizes and long-term follow-up is needed to confirm these findings.
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Registered trials
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