Evidence map›Paper›PMID 42420945›Full record

ArticleBMC public health2026

Workplace size and cardiovascular disease subtypes among 11 million Korean wage workers: a nationwide cross-sectional study.

Yangwoo Kim, Minji Koo, Eun Mi Kim, Jaiyong Kim, Inah Kim

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Article in BMC public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Yangwoo KimDepartment of Social and Preventive Medicine, Inha University College of Medicine, Incheon, Republic of Korea.
Minji KooDepartment of Artificial Intelligence, National Health Insurance Service, Wonju, Republic of Korea.
Eun Mi KimDepartment of Artificial Intelligence, National Health Insurance Service, Wonju, Republic of Korea.
Jaiyong KimDepartment of Big Data Management, National Health Insurance Service, Wonju, Republic of Korea.
Inah KimGraduate School of Public Health, Hanyang University, Seoul, Republic of Korea. inahkim@hanyang.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiovascular disease (CVD) encompasses distinct conditions whose risk factor profiles and socioeconomic gradients diverge. Workplace size is an administrative marker related to regulatory protections, health service access, and working conditions, but population-based evidence on whether CVD prevalence differs by subtype across workplace-size categories is limited. We examined the association between workplace size and the prevalence of 10 CVD subtypes among Korean wage workers.

methodsThis nationwide cross-sectional study included 11,212,512 Korean wage workers from the National Health Insurance Service database (2021). CVD cases were identified across 10 ICD-10 subtypes (I00-I99; three or more claims). Workplace size was classified into eight categories aligned with regulatory thresholds under the Korean Occupational Safety and Health Act. Logistic regression estimated adjusted odds ratios (aORs), controlling for sex and age, with the 5-29-worker category as reference. Sensitivity analyses applied hospitalization-based case definitions.

resultsCrude hypertensive disease (I10-I15) prevalence was highest in one-person workplaces (11,273.5 per 100,000), but after age and sex adjustment the crude OR of 1.12 changed direction to an aOR of 0.85 (95% CI 0.83-0.87). Mid-range workplaces (30-999 workers) showed the highest hypertensive disease aORs (up to 1.09). In contrast, ischemic heart disease (IHD; I20-I25) aORs were modestly elevated in the smallest workplaces (one-person: 1.12, 95% CI 1.05-1.19; 2-4-person: 1.05, 1.03-1.08), and cerebrovascular diseases (I60-I69) showed a modestly elevated aOR in the largest workplaces (1000 or more: 1.06, 1.03-1.08). Hospitalization-based sensitivity analyses showed IHD crude ORs remaining elevated and strengthening under more stringent criteria.

conclusionsThe association between workplace size and CVD prevalence was heterogeneous across subtypes. Hypertensive disease showed the highest adjusted prevalence in mid-range workplaces, a pattern consistent with demographic composition differences, whereas IHD and cerebrovascular diseases showed divergent prevalence patterns across workplace sizes. These findings indicate that the relationship between workplace size and CVD prevalence varies by subtype, with no uniform pattern across all workplace-size categories, and support disease-specific approaches to workplace-based cardiovascular surveillance. Because adjustment was limited to age and sex, these associations should be interpreted as descriptive prevalence patterns rather than causal effects.

Indexed as

Cardiovascular DiseasesWorkplaceAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceRepublic of KoreaRisk FactorsWorking ConditionsCardiovascular diseaseHealth inequalityOccupational healthWorkplace size

Identifiers

PMID42420945
PMCPMC13628708

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.