ArticleInnovation in aging2026
Cognitive trajectories of older adults before and after the COVID-19 pandemic: socioeconomic and psychological disparities in the Lc65+ cohort.
Article in Innovation in aging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and Objectives: The COVID-19 pandemic and related confinement measures have exacerbated health inequalities and posed unique challenges to cognitive aging. This study examined longitudinal changes in cognitive performance and associated factors before and after the COVID-19 pandemic, using data from the Swiss Lc65+ aging study. Methods: Analyses included participants with complete data across 3 assessment waves (2016-2024): 412 participants from Cohort 1 (born 1934-1938), 702 from Cohort 2 (born 1939-1943), and 826 from Cohort 3 (born 1944-1948), with women representing 58%-63% of each cohort. Cognitive performance was measured using the Mini-Mental State Examination (MMSE). Generalized estimating equations were used to evaluate changes in cognition and associations with socioeconomic, psychological, behavioral, and nutritional indicators. Results: Significant declines in MMSE scores were observed over time in Cohorts 1 and 2 ( Discussion and Implications: Findings indicate that the COVID-19 pandemic and confinement period coincided with accelerated cognitive decline and heightened socioeconomic vulnerability among older adults, particularly in the oldest cohort. Results highlight the need for multidimensional public health strategies.
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