ReviewCureus2026
Orthopaedic Oncology in Contemporary Practice: A Comprehensive Review of Primary Bone Tumours, Metastatic Pathways, and Evolving Surgical Techniques.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Orthopaedic oncology encompasses the diagnosis and management of primary bone sarcomas and metastatic skeletal disease, requiring integration of oncologic principles with complex musculoskeletal reconstruction. Advances in molecular classification, cross-sectional imaging, systemic therapy, and surgical technology have substantially transformed contemporary clinical practice. This comprehensive review synthesises current evidence across epidemiology, tumour biology, diagnostic strategies, staging systems, multidisciplinary management, reconstructive techniques, complication profiles, and survivorship considerations in modern orthopaedic oncology. Contemporary classification frameworks incorporating molecular and genetic insights have improved diagnostic precision and prognostic stratification. Structured staging systems and validated risk assessment tools facilitate clinical decision-making, particularly in metastatic bone disease, where the prediction of pathological fracture and mechanical instability guides prophylactic intervention. Progress in limb-salvage surgery, modular endoprosthetic reconstruction, intercalary replacement, biologic reconstruction, and technology-assisted resection has expanded functional preservation while maintaining oncologic safety. Integration of radiotherapy and systemic therapies, including targeted and multimodal regimens, has enhanced survival in selected malignancies, shifting emphasis toward durable reconstruction and quality-of-life outcomes. Persistent challenges include tumour heterogeneity, infection and mechanical complications, and variability in long-term functional reporting. Contemporary orthopaedic oncology is defined by multidisciplinary coordination and biologically informed surgical strategy. Continued refinement of molecular stratification, standardised outcome assessment, and technological innovation remains essential to optimise oncologic control and functional recovery in patients with primary and metastatic bone tumours.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.