ReviewJournal of basic microbiology2026
Next-Generation Cyanobacterial Biocontrol Agents for Crop Fungal Diseases: Molecular Mechanisms, Omics Insights, Applications, and Biosafety Considerations.
Review in Journal of basic microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Fungal diseases are major constraint to global crop production, causing substantial losses and increasing reliance on chemical fungicides. Cyanobacteria offers a sustainable alternative for disease managment due to their ability to produce antifungal metabolites, including volatile organic compounds (VOCs), exopolysaccharides (EPS), and lytic enzymes. These bioactive molecules suppress phytopathogenic fungi by disrupting cell membranes, inhibiting virulence factors, inducing oxidative stress, and degrading cell wall components. Cyanobacteria also enhance plant defence responses by activating salicylic acid (SA), jasmonic acid (JA), ethylene, and nitric oxide (NO) signaling pathways, leading to upregulation of defense-related genes, including PR proteins, PAL, and WRKY transcription factors. Recent multi-omics approaches have provided valuable insights into biosynthetic gene clusters, regulatory networks, and metabolic pathways underlying cyanobacterial antifungal activity. Although laboratory evidence is encouraging, field application remains challenging by environmental variability and formulation limitations. Emerging advances in genome mining and synthetic biology may enhance the effectiveness of cyanobacterial biocontrol agents. This review highlights current progress in cyanobacteria-mediated management of fungal diseases, discusses biosafety considerations, and outlines future research directions for developing eco-friendly and sustainable crop protection solutions.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.