Evidence map›Paper›PMID 42423332›Full record

ArticleJACC. Case reports2026

Cross-Organ Recovery After Transcatheter Tricuspid Valve Replacement With Diuretic and Antiviral Discontinuation: Beyond Cardiac Function.

Adham Sameer A Bardeesi, Aiman Ghrab, Julien Ternacle, Lukas Weber, Pierre Jeantet, Lionel Leroux, Guillaume Bonnet, Thomas Modine

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Adham Sameer A BardeesiMedical-Surgical Unit for Valvular Heart Disease, Department of Cardiology and Cardiovascular Surgery, Haut-Lévêque Cardiology Hospital, Bordeaux University Hospital (CHU), Pessac, France; Department of Cardiac Surgery, King Fahad Specialist Hospital Damman, Saud Al-Babtain Cardiac Center, Dammam, Saudi Arabia.
Aiman GhrabMedical-Surgical Unit for Valvular Heart Disease, Department of Cardiology and Cardiovascular Surgery, Haut-Lévêque Cardiology Hospital, Bordeaux University Hospital (CHU), Pessac, France; Cardiology Department, Hedi Chaker, University Hospital of Sfax, Sfax, Tunisia.
Julien TernacleMedical-Surgical Unit for Valvular Heart Disease, Department of Cardiology and Cardiovascular Surgery, Haut-Lévêque Cardiology Hospital, Bordeaux University Hospital (CHU), Pessac, France.
Lukas WeberMedical-Surgical Unit for Valvular Heart Disease, Department of Cardiology and Cardiovascular Surgery, Haut-Lévêque Cardiology Hospital, Bordeaux University Hospital (CHU), Pessac, France.
Pierre JeantetMedical-Surgical Unit for Valvular Heart Disease, Department of Cardiology and Cardiovascular Surgery, Haut-Lévêque Cardiology Hospital, Bordeaux University Hospital (CHU), Pessac, France.
Lionel LerouxMedical-Surgical Unit for Valvular Heart Disease, Department of Cardiology and Cardiovascular Surgery, Haut-Lévêque Cardiology Hospital, Bordeaux University Hospital (CHU), Pessac, France.
Guillaume BonnetMedical-Surgical Unit for Valvular Heart Disease, Department of Cardiology and Cardiovascular Surgery, Haut-Lévêque Cardiology Hospital, Bordeaux University Hospital (CHU), Pessac, France.
Thomas ModineMedical-Surgical Unit for Valvular Heart Disease, Department of Cardiology and Cardiovascular Surgery, Haut-Lévêque Cardiology Hospital, Bordeaux University Hospital (CHU), Pessac, France. Electronic address: thomas.modine@chu-bordeaux.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTranscatheter tricuspid valve replacement (TTVR) is an emerging option for patients with severe tricuspid regurgitation (TR) at prohibitive surgical risk. Severe TR is associated with systemic venous congestion, multiorgan dysfunction, and high mortality, yet isolated tricuspid surgery is rarely performed. CASE SUMMARY: A 68-year-old woman with prior double mechanical valve replacement, chronic kidney disease, and hepatitis B, treated with entecavir, presented with dyspnea and edema. Imaging revealed torrential TR with a 43-mm annulus. Because of high surgical risk, she underwent successful TTVR. TR abolition allowed cessation of diuretics and antiviral therapy after normalization of hepatic tests and viral load. DISCUSSION: This case illustrates how TTVR-mediated venous decongestion can reverse renal and hepatic alterations and enable cessation of supportive therapies. TAKE-HOME MESSAGES: TTVR can abolish TR, improve right-heart hemodynamics, and provide systemic benefits beyond cardiac function. Venous decongestion may enable cross-organ recovery and allow withdrawal of diuretics and antiviral therapy.

Indexed as

diuretic withdrawalhepatic recoveryhepatitis BLuxValvetranscatheter tricuspid valve replacementtricuspid regurgitationvenous congestion

Identifiers

PMID42423332
PMCPMC13350394

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.