Evidence map›Paper›PMID 42423564›Full record

ArticleClinical cardiology2026

The Association Between Bending Photoplethysmography Waveform Area Index and Congestive Heart Failure.

Xianghui Zeng, Qingfeng Zeng, Chunqing Xiao, Hengqing Zhu, Jianping Luo

Abstract read
In one paragraph

Article in Clinical cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xianghui ZengDepartment of Cardiology, Ganzhou Hospital of Traditional Chinese Medicine, Ganzhou, Jiangxi, China.ORCID https://orcid.org/0000-0002-9372-1063
Qingfeng ZengDepartment of Cardiology, Ganzhou Hospital of Traditional Chinese Medicine, Ganzhou, Jiangxi, China.ORCID https://orcid.org/0000-0002-6575-8467
Chunqing XiaoDepartment of Cardiology, Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, Jiangxi, China.ORCID https://orcid.org/0000-0002-7654-5707
Hengqing ZhuDepartment of Cardiology, Ganzhou Hospital of Guangdong Provincial People's Hospital, Ganzhou Municipal Hospital, Ganzhou, Jiangxi, China.
Jianping LuoDepartment of Cardiology, Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, Jiangxi, China.ORCID https://orcid.org/0000-0003-2016-9535

Funding

Science and Technology Bureau of Ganzhou City, China 50 [2018]Scientific Research Project of Health Committee of Jiangxi Province 202611483
6 · The paper itself

Abstract

aimsCongestive heart failure (CHF) is closely associated with a decrease in cardiac output, and photoplethysmography (PPG) parameters can experimentally assess cardiac output. It is unclear whether there is an association between the change of bending photoplethysmography waveform area index (BPWAI) due to postural changes and CHF.

methodsWe enrolled patients with suspected CHF. Patients completed physical examination, echocardiography, and pro-brain natriuretic peptide (NT-proBNP) test during their visit, and finger-end PPG waveform area was measured in the sitting and bending positions using PPG. We then used logistic regression to analyze the association between BPWAI and CHF, and the receiver operating characteristic (ROC) curve and area under the curve (AUC) were used to assess the event risk association strength.

resultsA total of 523 patients with suspected CHF were included in this study, of whom 291 (55.6%) had a final diagnosis of CHF. The association between BPWAI and CHF decreased 0.45-fold for per 1 standard deviation increase in BPWAI (OR: 0.55 [95% CI, 0.44-0.68]). The AUC for BPWAI associated with CHF was 0.736 (95% CI, 0.689-0.782), with a corresponding sensitivity of 67.4% and specificity of 71.5%, and a cut-off value of 0.85 for the diagnosis of CHF.

conclusionWhen patients bend over, their PPG waveform area decreases, which is closely associated with patients with CHF. BPWAI is significantly associated with CHF and may serve as a potential associated indicator for CHF.

Indexed as

Cardiac OutputHeart FailurePhotoplethysmographyPostureAgedArea Under CurveBiomarkersFemaleHumansMaleMiddle AgedNatriuretic Peptide, BrainPeptide FragmentsPredictive Value of TestsRisk FactorsROC CurveBiomarkersNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)bendingcongestive heart failurediagnostic markerphotoplethysmography waveform areasitting

Identifiers

PMID42423564
PMCPMC13348781

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.