Evidence map›Paper›PMID 42424614›Full record

ArticleJournal of neurophysiology2026

Persistent input- and cell-type-specific synaptic alterations in the somatosensory thalamus of Dravet syndrome mice.

Mona Safari, Rutvi Pallav Desai, Harbal Rai, Tyler J Roberts, Rabeya Khondaker, Julia Smith, Sharon A Swanger

Abstract read
In one paragraph

Article in Journal of neurophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mona SafariFralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, Virginia, United States.ORCID 0000-0001-5608-9524
Rutvi Pallav DesaiFralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, Virginia, United States.ORCID 0009-0004-7001-6507
Harbal RaiFralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, Virginia, United States.
Tyler J RobertsFralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, Virginia, United States.ORCID 0009-0009-0078-8970
Rabeya KhondakerFralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, Virginia, United States.
Julia SmithFralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, Virginia, United States.
Sharon A SwangerFralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, Virginia, United States.ORCID 0000-0003-0615-6244

Funding

Molecular and functional diversity of NMDA receptors in the thalamusR01NS105804 · NINDS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI SWANGER, SHARON ANN · 2019 to 2023
$1.7M
Brain Research Foundation (BRF) BRFSG-2021-10Commonwealth Health Research Board (CHRB) 208-08-24HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) NS105804NINDS NIH HHS R01 NS105804Seale Innovation Fund
6 · The paper itself

Abstract

Dravet syndrome (DS) is an epileptic encephalopathy most often caused by loss-of-function mutations in the

Indexed as

Epilepsies, MyoclonicNeuronsSynapsesThalamusAnimalsDisease Models, AnimalExcitatory Postsynaptic PotentialsFemaleMaleMiceMice, Inbred C57BLNAV1.1 Voltage-Gated Sodium ChannelSomatosensory CortexNAV1.1 Voltage-Gated Sodium ChannelScn1a protein, mousecorticothalamicDravet syndromeSCN1Asomatosensory thalamussynaptic transmission

Identifiers

PMID42424614
PMCPMC13533332

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.