ArticleBMJ open2026
BEnefit of HYpnosis on Pain during stitches in an Emergency Room: a study protocol using a randomised controlled trial - the BE-HYPER protocol.
Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06497712 (BEnefit of HYpnosis on Pain During Stitches in Emergency Room), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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BEnefit of HYpnosis on Pain During Stitches in Emergency Room: The BE-HYPER Study
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0 citing papers in PubMed.
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionWounds are one of the most common causes of emergency department visits. Their care often involves stitches, a potentially painful and stressful procedure. Pain and stress management is usually based on local anaesthesia, which is not always optimal. Medical hypnosis may offer a non-pharmacological alternative. Heart rate variability is a pain-free, easy-to-use and objective biomarker of stress. This study aims to assess the benefit of hypnosis on stress and pain during stitching using a randomised controlled trial. METHODS AND ANALYSIS: This is a single-centre, randomised controlled trial in an emergency department in Clermont-Ferrand. Patients consulting for suturable wounds will be randomised into two groups: with or without medical hypnosis. Measurements will include questionnaires, heart rate variability, physical activity levels and blood biomarkers. The primary outcome is heart rate variability during the procedure. Data will be analysed with intention-to-treat and per-protocol approaches, with p<0.05 considered statistically significant. ETHICS AND DISSEMINATION: The study has received approval from the Ethics Committee Sud-Méditerranée III, France, and is registered on ClinicalTrials.gov. Written informed consent will be obtained from all participants. Results will be published in a peer-reviewed journal. TRIAL REGISTRATION NUMBER: NCT06497712.
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