Evidence map›Paper›PMID 42426828›Full record

ArticleExperimental hematology & oncology2026

Cystathionine beta-synthase promotes anoikis resistance and transcoelomic metastasis in ovarian cancer via SP1- ITGB1 regulation.

Pallab Shaw, Arpan Dey Bhowmik, Akrit Pran Jaswal, Rameswari Velayutham, Srikanth Chiliveru, Samantha Ricketts, Chao Xu, Danny N Dhanasekaran, Zhizhaung Joe Zhao, Resham Bhattacharya and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental hematology & oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Pallab ShawOU Health Stephenson Cancer Center, The University of Oklahoma Health Campus, 1122 NE 13th St, O'Donoghue Research Building #335B, OK, 73117, Oklahoma City, USA.
Arpan Dey BhowmikOU Health Stephenson Cancer Center, The University of Oklahoma Health Campus, 1122 NE 13th St, O'Donoghue Research Building #335B, OK, 73117, Oklahoma City, USA.
Akrit Pran JaswalOU Health Stephenson Cancer Center, The University of Oklahoma Health Campus, 1122 NE 13th St, O'Donoghue Research Building #335B, OK, 73117, Oklahoma City, USA.
Rameswari VelayuthamDepartment of Pathology, The University of Oklahoma Health Campus, Oklahoma City, OK, 73104, USA.
Srikanth ChiliveruOU Health Stephenson Cancer Center, The University of Oklahoma Health Campus, 1122 NE 13th St, O'Donoghue Research Building #335B, OK, 73117, Oklahoma City, USA.
Samantha RickettsDepartment of Pathology, The University of Oklahoma Health Campus, Oklahoma City, OK, 73104, USA.
Chao XuOU Health Stephenson Cancer Center, The University of Oklahoma Health Campus, 1122 NE 13th St, O'Donoghue Research Building #335B, OK, 73117, Oklahoma City, USA.
Danny N DhanasekaranOU Health Stephenson Cancer Center, The University of Oklahoma Health Campus, 1122 NE 13th St, O'Donoghue Research Building #335B, OK, 73117, Oklahoma City, USA.
Zhizhaung Joe ZhaoDepartment of Pathology, The University of Oklahoma Health Campus, Oklahoma City, OK, 73104, USA.
Resham BhattacharyaOU Health Stephenson Cancer Center, The University of Oklahoma Health Campus, 1122 NE 13th St, O'Donoghue Research Building #335B, OK, 73117, Oklahoma City, USA.
Priyabrata MukherjeeOU Health Stephenson Cancer Center, The University of Oklahoma Health Campus, 1122 NE 13th St, O'Donoghue Research Building #335B, OK, 73117, Oklahoma City, USA.
Shailendra Kumar Dhar DwivediOU Health Stephenson Cancer Center, The University of Oklahoma Health Campus, 1122 NE 13th St, O'Donoghue Research Building #335B, OK, 73117, Oklahoma City, USA.
Geeta RaoOU Health Stephenson Cancer Center, The University of Oklahoma Health Campus, 1122 NE 13th St, O'Donoghue Research Building #335B, OK, 73117, Oklahoma City, USA. geeta-rao@ou.edu.

Funding

Tissue Pathology Shared ResourceP30CA225520 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI ROBERT S. MANNEL · 2018 to 2026
$27.1M
Use of 3D Quantitative Optical Methods to Optimize Mebendazole Treatment of Ovarian CancerP20GM135009 · NIGMS · UNIVERSITY OF OKLAHOMA · PI Javier Antonio Jo · 2022 to 2026
$13.6M
American Cancer Society Institutional Research Grant ACS-IRG-23-1143225-04-IRGNCI NIH HHS P30 CA225520NIGMS NIH HHS P20 GM135009
6 · The paper itself

Abstract

Anoikis resistance is crucial for ovarian cancer (OvCa) transcoelomic metastasis, during which exfoliated OvCa cells survive as spheroids before invading the omentum. Here, we demonstrate that cystathionine β-synthase (CBS), an H

Indexed as

2D 3D cultureAnoikis resistanceCystathionine β-synthase (CBS)Integrin β1 (ITGB1)Ovarian cancer spheroidsTranscoelomic metastasis

Identifiers

PMID42426828
PMCPMC13579884

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.