Evidence map›Paper›PMID 42427782›Full record

ArticlebioRxiv : the preprint server for biology2026

PIP

Kirin D Gada, Jordie M Kamuene, Ana Santa Cruz, Ziyue Meng, Jenna G Connolly, Florence Ng, Xinyi Ma, Aishwarya Chandrashekar, Yu Xu, Meng Cui and 1 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kirin D GadaDepartment of Pharmaceutical and Biomedical Sciences, School of Pharmacy and Pharmaceutical Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, MA 02115.
Jordie M KamueneDepartment of Pharmaceutical and Biomedical Sciences, School of Pharmacy and Pharmaceutical Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, MA 02115.
Ana Santa CruzDepartment of Pharmaceutical and Biomedical Sciences, School of Pharmacy and Pharmaceutical Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, MA 02115.
Ziyue MengDepartment of Pharmaceutical and Biomedical Sciences, School of Pharmacy and Pharmaceutical Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, MA 02115.
Jenna G ConnollyDepartment of Pharmaceutical and Biomedical Sciences, School of Pharmacy and Pharmaceutical Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, MA 02115.
Florence NgDepartment of Pharmaceutical and Biomedical Sciences, School of Pharmacy and Pharmaceutical Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, MA 02115.
Xinyi MaDepartment of Pharmaceutical and Biomedical Sciences, School of Pharmacy and Pharmaceutical Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, MA 02115.
Aishwarya ChandrashekarDepartment of Pharmaceutical and Biomedical Sciences, School of Pharmacy and Pharmaceutical Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, MA 02115.
Yu XuDepartment of Pharmaceutical and Biomedical Sciences, School of Pharmacy and Pharmaceutical Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, MA 02115.
Meng CuiDepartment of Pharmaceutical and Biomedical Sciences, School of Pharmacy and Pharmaceutical Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, MA 02115.
Leigh D PlantDepartment of Pharmaceutical and Biomedical Sciences, School of Pharmacy and Pharmaceutical Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, MA 02115.ORCID 0000-0002-1622-1655

Funding

SUMO-regulation of ion channels via PIP2R01HL144615 · NHLBI · NORTHEASTERN UNIVERSITY · PI PLANT, LEIGH DANIEL · 2019 to 2022
$1.6M
NHLBI NIH HHS R01 HL144615
6 · The paper itself

Abstract

The cardiac sodium channel Na

Indexed as

angiotensin IIarrhythmiachannelopathyGq signalinglate sodium currentNaV1.5 channelphosphoinositide regulationPIP2

Identifiers

PMID42427782
PMCPMC13345292

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.