Evidence map›Paper›PMID 42428146›Full record

ReviewFrontiers in oncology2026

Global stomach cancer burden from high-sodium diet and smoking: 1990-2021 findings & 2040 projections.

Xiaodie Zhou, Xiaoying Han, Shiliang Dong, Mini Han Wang, Ethan Zhiyuan Lin, Hoiman Ng, Chonin Cheang

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaodie Zhou *Gastrointestinal Disease Diagnosis and Treatment Center, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, China.
Xiaoying Han *Gastrointestinal Disease Diagnosis and Treatment Center, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, China.
Shiliang DongDepartment of Gastrointestinal and Bariatric Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Mini Han WangFrontier Computing Center, Zhuhai Institute of Advanced Technology Chinese Academy of Sciences, Zhuhai, China.
Ethan Zhiyuan LinOmniContext AI Lab, Hong Kong, Hong Kong SAR, China.
Hoiman NgClinical Laboratory, Kiang Wu Hospital, Macao, Macao SAR, China.
Chonin CheangDepartment of Gastrointestinal and Bariatric Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Stomach cancer remains a major global health burden, and high sodium intake and smoking are key modifiable risk factors, yet their long-term and future contributions to global mortality and disability remain unclear. Objective: (1) assess the global burden of stomach cancer linked to high sodium intake and smoking from 1990 to 2021; (2) forecast the burden from 2021 to 2040. Methods: We used Global Burden of Disease 2021 data to calculate age- and sex-specific death and DALYs rates, percentage changes, and population attributable fractions for high sodium intake and smoking. Results: In 2021, 7.9% and 11.2% of global age-standardized stomach cancer deaths were attributed to high sodium intake and smoking, respectively, with men and older adults most affected. East Asia had the highest death and DALY rates, and High-income North America and Western Sub-Saharan Africa the lowest; Mongolia and Bolivia topped sodium-related rates, while Morocco and Nigeria were lowest. From 1990 to 2021, sodium-related mortality rose most in Egypt and fell most in South Korea; smoking-related deaths rose in Egypt and Lesotho but fell in Singapore. High-middle SDI regions bore the greatest burden, and projections to 2040 predict global declines in death and DALY rates for both risks. Conclusions: Our findings highlight the need for targeted, region- and gender-specific policies to curb stomach cancer risk from high sodium intake and smoking, providing policymakers with vital data for effective public health interventions.

Indexed as

global burden of disease (GBD)smokingsocio-demographic index (SDI)sodium intakestomach cancer

Identifiers

PMID42428146
PMCPMC13347218

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.