ArticleFrontiers in microbiology2026
Genomic and resistome characterization of a multidrug-resistant
Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Methods: We conducted integrated epidemiological and environmental traceback investigations. Whole-genome sequencing (WGS) and core-genome multilocus sequence typing (cgMLST) were applied to analyze the genetic relatedness and resistome of the recovered isolates. Results: Traceback strongly implicated rice noodles as the most likely vehicle. The outbreak was traced to a prerequisite program failure (raw clam exudate dripping onto uncovered noodles) followed by a critical control point failure (insufficient blanching for 1-2 min). WGS and cgMLST supported these findings: clinical and rice-noodle isolates were genetically identical (0-1 SNPs, Conclusion: These results indicate that cross-contaminated food matrices can act as reservoirs for clinically relevant resistance determinants. This underscores the need for strict physical barriers, validated thermal processing, and high-resolution genomic surveillance to prevent opportunistic pathogen transmission in commercial catering.
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