Evidence map›Paper›PMID 42428574›Full record

ArticleRegenerative biomaterials2026

An electroactive platform enabled by near-field communication for accelerating infected diabetic wound healing via directional electric field reshaping and immunomodulation.

Yuange Zong, Ying Chen, Kexin Deng, Peng Zheng, Hongling Zhou, Ze Zhang, Wanqi Huang, Danyang Huang, Yuan Peng, Jiaping Zhang

Abstract read
In one paragraph

Article in Regenerative biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuange ZongDepartment of Plastic Surgery, State Key Laboratory of Trauma and Chemical Poisoning, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Ying ChenDepartment of Plastic Surgery, State Key Laboratory of Trauma and Chemical Poisoning, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Kexin DengDepartment of Plastic Surgery, State Key Laboratory of Trauma and Chemical Poisoning, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Peng ZhengDepartment of Plastic Surgery, State Key Laboratory of Trauma and Chemical Poisoning, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Hongling ZhouDepartment of Plastic Surgery, State Key Laboratory of Trauma and Chemical Poisoning, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Ze ZhangDepartment of Plastic Surgery, State Key Laboratory of Trauma and Chemical Poisoning, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Wanqi HuangDepartment of Plastic Surgery, State Key Laboratory of Trauma and Chemical Poisoning, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Danyang HuangDepartment of Plastic Surgery, State Key Laboratory of Trauma and Chemical Poisoning, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Yuan PengDepartment of Plastic Surgery, State Key Laboratory of Trauma and Chemical Poisoning, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing 400038, China.
Jiaping ZhangDepartment of Plastic Surgery, State Key Laboratory of Trauma and Chemical Poisoning, Southwest Hospital, Army Medical University (Third Military Medical University), Chongqing 400038, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrical stimulation for diabetic wound healing predominantly relies on wired power supplies, which not only increase the risk of secondary infection and complicate clinical operation but may also misalign with the endogenous bioelectric field (EF), collectively limiting effective tissue repair. To address the above limitations, we developed a portable hydrogel dressing wirelessly powered by near-field communication (NFC) through mobile phones, which produces electrical stimulation in precise alignment with the EF and thus effectively facilitates diabetic wound repair. Mechanistic studies reveal that the reconstructed directional biomimetic electric field significantly activates the Phosphatidylinositol 3-kinase/AKT (PI3K/AKT) signaling pathway within the wound tissue microenvironment, thereby reshaping the immune response pattern and restoring immune homeostasis. Simultaneously, the hydrogel dressing efficiently promotes the migration and proliferation of epidermal cells and induces neovascularization, providing essential structural support for wound repair. By integrating wireless NFC technology with directional bioelectric field therapy, this study provides a novel paradigm for the repair of clinically refractory infected diabetic wounds and demonstrates significant value for clinical translation and application.

Indexed as

bioelectric fieldselectroactive hydrogelsinfected diabetic woundsintrinsic self-antibacterialnear-field communication

Identifiers

PMID42428574
PMCPMC13346114

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.