ArticleCirculation reports2026
Skeletal Muscle Oxygenation During Exercise and Its Association With Early Improvement in Exercise Tolerance After Transcatheter Aortic Valve Implantation.
Article in Circulation reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: This study aimed to: (1) assess changes in peripheral skeletal muscle oxygenation during exercise after transcatheter aortic valve implantation (TAVI) in patients with severe aortic stenosis (AS); and (2) identify characteristics of patients who exhibited improved exercise tolerance. Methods and Results: In this single-center prospective study, 20 patients with severe symptomatic AS underwent evaluation before and 1 week after TAVI. Exercise tolerance was assessed using the incremental shuttle walk test (ISWT), and the incremental shuttle walk distance (ISWD) was recorded. Calf muscle oxygenation during the ISWT was continuously measured using near-infrared spectroscopy (NIRS). ISWD increased significantly after TAVI (P<0.01). During the ISWT, the change in oxygenated hemoglobin (∆O Conclusions: Peripheral skeletal muscle oxygenation during exercise improved early after TAVI. Moreover, a pre-TAVI pattern characterized by reduced oxygen delivery (lower ∆O
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