Evidence map›Paper›PMID 42428670›Full record

ArticleFrontiers in endocrinology2026

Associations of MALAT1 rs619586/rs3200401 and ANRIL rs10965215/rs10738605 polymorphisms with type 2 diabetes and diabetic nephropathy risk in an Egyptian population.

Marwa A Ali, Omayma O Abdealeem, Olfat G Shaker, Mahmoud G Algammal, Nada F Hemeda, Doaa Y Ali, Mohammed Makloph, Mohamed M Mohamed, Ahmed Magdy Elebiary, Asmaa Saleh and 3 more

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Article in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Marwa A AliDepartment of Biomedical Sciences, College of Medicine, King Faisal University, Al-Ahsa, Saudi Arabia.
Omayma O AbdealeemDepartment of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Fayoum University, Fayoum, Egypt.
Olfat G ShakerDepartment of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Mahmoud G AlgammalDepartment of Internal Medicine, Faculty of Medicine, Fayoum University, Fayoum, Egypt.
Nada F HemedaDepartment of Genetics, Faculty of Agriculture, Fayoum University, Fayoum, Egypt.
Doaa Y AliDepartment of Clinical and Chemical Pathology, Faculty of Medicine, Fayoum University, Fayoum, Egypt.
Mohammed MaklophDepartment of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Fayoum University, Fayoum, Egypt.
Mohamed M MohamedDepartment of Internal Medicine, Faculty of Medicine, Cairo University, Cairo, Egypt.
Ahmed Magdy ElebiaryDepartment of Physiology, Faculty of Medicine, Fayoum University, Fayoum, Egypt.
Asmaa SalehDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Marwa KamalDepartment of Clinical Pharmacy, Faculty of Pharmacy, Fayoum University, Fayoum, Egypt.
Noura Mostafa MohamedDepartment of Basic Sciences, College of Medicine, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Thanaa A El-MasryPharmacology and Toxicology Department, Faculty of Pharmacy, Tanta University, Tanta, Al-Gharbia, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diabetic nephropathy (DN) is a serious microvascular complication of type 2 diabetes mellitus (T2DM).Single-nucleotide polymorphisms (SNPs) in long non-coding RNAs Objective: To investigate the association of Methods: This case-control study included 64 T2DM patients, 75 DN patients, and 70 healthy controls from Fayoum University Hospital. Genomic DNA was extracted from peripheral blood, and SNP genotyping was performed using TaqMan real-time PCR. All analyses were adjusted for age and sex. The study had 80% power to detect associations based on expected differences in allele frequencies. Results: Conclusions:

Indexed as

Diabetes Mellitus, Type 2Diabetic NephropathiesGenetic Predisposition to DiseasePolymorphism, Single NucleotideRNA, Long NoncodingAdultCase-Control StudiesEgyptFemaleGene FrequencyGenotypeHumansMaleMiddle AgedRisk FactorsCDKN2B antisense RNA, humanMALAT1 long non-coding RNA, humanRNA, Long Noncodingdiabetes mellitusdiabetic nephropathyrs10738605rs10965215rs3200401rs619586

Identifiers

PMID42428670
PMCPMC13346653

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.