Evidence mapPaperPMID 42428676Full record

SynthesisFrontiers in aging neuroscience2026

Aerobic exercise interventions for older adults with cognitive frailty: a systematic review.

Xu Zhou, Lin Chen, Zheng Huang, Zihao Zhang, Meng Li, Zhongfang Yang

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in aging neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xu ZhouDepartment of Orthopaedics, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Lin ChenDepartment of Orthopaedics, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zheng HuangNursing Department, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zihao ZhangDepartment of Orthopaedics, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Meng LiSchool of Nursing, Gansu University of Chinese Medicine, Lanzhou, Gansu, China.
Zhongfang YangSchool of Nursing, Suzhou Medical College of Soochow University, Suzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The purpose of this study was to systematically review the effects of aerobic exercise on cognitive function in older adults using randomized controlled trials (RCTs). Design: This study was a systematic review. Data sources: Ten databases, namely PubMed, the Cochrane Library, Wanfang, China National Knowledge Infrastructure (CNKI), SinoMed, Medline, Embase, the Social Science Citation Index (SSCI), Bielefeld Academic Search Engine (BASE), and OpenGrey, were searched from their inception to 30 April 2026. The qualification standard of the selective study: The randomized controlled trials of the aerobic exercise interventions for the cognitive function of older adults were addressed. Results: A total of 16 studies were included in the review. The primary conclusion of the quoted studies was that they evaluated the effects of interventions on cognitive function. Many studies (68.8%) used a single-blinded design, while 6.3% used a double-blind design and 25% used an open-label design. Overall, 14 studies (87.5%) reported significant cognitive benefits. Interventions were classified as pure aerobic ( Conclusion: These findings prove that aerobic exercise benefits cognition, verbal fluency, attention, sleep quality, executive function, flanker task reaction time, and postural balance. Simultaneous dual-task aerobic exercise may yield larger executive and memory gains than lower-cognitive-load activities. Systematic review registration: PROSPERO, CRD420251061109.

Indexed as

aerobic exerciseChinese traditional medicinecognitive functionfrailtyolder adults

Identifiers

PMID42428676
PMCPMC13345865

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.