Evidence map›Paper›PMID 42428725›Full record

ReviewIranian journal of public health2025

The Microbial Factors, Trace Elements, and Important Biological Indicators in Children with Autism Spectrum Disorder: A Meta-Analysis.

Keli Qu, Zhiliang Gao, Cong Chang, Meizhe Gao

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Iranian journal of public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Keli QuDepartment of Child Healthcare, Shandong Provincial Third Hospital, Shandong University, Jinan, China.
Zhiliang GaoDepartment of Pediatric, Binzhou Hospital of Traditional Chinese Medicine, Binzhou, China.
Cong ChangDepartment of Rehabilitation, Binzhou Municipal Hospital, Binzhou, China.
Meizhe GaoDepartment of Child Healthcare, Shandong Provincial Third Hospital, Shandong University, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We examined and compared microbiological variables, trace elements, and biological markers in autistic children. Methods: Several databases, including the Cochrane Library, PubMed, OVID, Google Scholar, and Embase, were utilized for data collection and analysis. We studied meta-analysis data and used a continuous model with fixed or random effects to get mean differences (MD) with 95% confidence intervals (CIs). Twenty-seven studies involving 2557 children from 2014 to 2024 were analyzed. Results: Autism spectrum disorder had significantly higher C-reactive protein (MD, 1.25; 95% CI, 0.11^ndash;2.39, Conclusion: Autism spectrum disorder had significantly higher C-reactive protein, interleukin-6, serotonin,

Indexed as

Autism spectrum disorderImportant biological indicatorMicrobial factorSerotoninTrace element

Identifiers

PMID42428725
PMCPMC13348885

What Socratic holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.