SynthesisFrontiers in bioengineering and biotechnology2026
Eggshell membrane-based biomaterials for tissue regeneration: a systematic review of preclinical evidence.
Synthesis in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Limitations of conventional wound dressings have spurred the exploration of regenerative biomaterials capable of actively promoting tissue repair. Eggshell membrane (ESM) is emerging as a low-cost, biocompatible scaffold with significant potential in advanced wound care applications. Aim: To evaluate the therapeutic potential of ESM-based wound dressings in enhancing the wound-healing process. Methods: A systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Comprehensive searches were performed across PubMed, Scopus, ScienceDirect, and ProQuest, covering all records up to 22 June 2024. Only English-language studies investigating eggshell membrane as a wound care biomaterial were included. Study selection adhered to predefined eligibility and inclusion criteria. Results: From 599 identified records, 36 studies met the inclusion criteria. Fifteen studies involved Conclusion: This review highlights the considerable potential of eggshell membrane-based dressings as regenerative biomaterials for the management of complex wounds. While ESM shows strong promise as a scaffold for wound healing, further standardized and clinically focused research is necessary to establish robust evidence supporting its translational and therapeutic applications. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420260551038, identifier CRD420260551038.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.