Evidence map›Paper›PMID 42429166›Full record

ArticleAngewandte Chemie (International ed. in English)2026

Unified Synthesis of Unconventional α-Polyhalogenated Amines Through Hydroaminoalkylation.

Angela K Hofmeister, Giulia Iannelli, Péter Angyal, Augustin Malandain, Daniel Kaiser, Boris Maryasin, Hanspeter Kählig, Matteo Barel, Gaia Novarino, Nuno Maulide

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Angela K HofmeisterInstitute of Organic Chemistry, University of Vienna, Vienna, Austria.
Giulia IannelliInstitute of Organic Chemistry, University of Vienna, Vienna, Austria.
Péter AngyalInstitute of Organic Chemistry, University of Vienna, Vienna, Austria.
Augustin MalandainInstitute of Organic Chemistry, University of Vienna, Vienna, Austria.
Daniel KaiserInstitute of Organic Chemistry, University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0001-8895-9969
Boris MaryasinInstitute of Organic Chemistry, University of Vienna, Vienna, Austria.
Hanspeter KähligInstitute of Organic Chemistry, University of Vienna, Vienna, Austria.
Matteo BarelInstitute of Science and Technology Austria, Klosterneuburg, Austria.ORCID https://orcid.org/0000-0002-2894-8608
Gaia NovarinoInstitute of Science and Technology Austria, Klosterneuburg, Austria.
Nuno MaulideInstitute of Organic Chemistry, University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0003-3643-0718

Funding

Austrian Science Fund 10.55776/P37182European Research CouncilEuropean Union
6 · The paper itself

Abstract

We report a unified method for the synthesis of α-polyhalomethyl amines from alkenes and alkynes, enabled by readily available hemiaminal reagents. This operationally simple transformation allows for the introduction of not only well-established CF

Indexed as

aminationdifluoromethylpolyhalogenationunactivated alkenesα‐halomethyl amines

Identifiers

PMID42429166
PMCPMC13573030

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.