Evidence map›Paper›PMID 42429181›Full record

ArticleAngewandte Chemie (International ed. in English)2026

Minute-Scale Repeated Metabolic Probing of Living Cells Enabled by Rapid Parahydrogen-Based Hyperpolarization.

Philipp R Groß, Stefan Petersen, Zirun Wang, Behnam Shamshiri, Henri de Maissin, Sebastian Lucas, Oliver Gorka, Lisa Heß, Irene Marco-Rius, Lluís Mangas-Florencio and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Hyperpolarization of [1-Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Philipp R GroßDivision of Medical Physics, Department of Radiology, Medical Center and Faculty of Medicine, Freiburg, Germany.
Stefan PetersenDivision of Medical Physics, Department of Radiology, Medical Center and Faculty of Medicine, Freiburg, Germany.
Zirun WangDivision of Medical Physics, Department of Radiology, Medical Center and Faculty of Medicine, Freiburg, Germany.
Behnam ShamshiriDivision of Medical Physics, Department of Radiology, Medical Center and Faculty of Medicine, Freiburg, Germany.
Henri de MaissinDivision of Medical Physics, Department of Radiology, Medical Center and Faculty of Medicine, Freiburg, Germany.
Sebastian LucasNVision Imaging Technologies GmbH, Ulm, Germany.
Oliver GorkaFaculty of Medicine, Medical Center, Institute of Neuropathology, University of Freiburg, Freiburg, Germany.
Lisa HeßInstitute of Molecular Medicine and Cell Research, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Irene Marco-RiusInstitute For Bioengineering of Catalonia (IBEC), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.ORCID 0000-0001-5076-8526
Lluís Mangas-FlorencioInstitute For Bioengineering of Catalonia (IBEC), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
André F MartinsDepartment of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Eberhard Karls University Tübingen, Tübingen, Germany.ORCID 0000-0002-0171-0261
Philipp Boehm-SturmCharité 3R - Replace, Reduce, Refine, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Maxim ZaitsevDivision of Medical Physics, Department of Radiology, Medical Center and Faculty of Medicine, Freiburg, Germany.
Robert ZeiserGerman Cancer Consortium (DKTK), Partner Site Freiburg, a Partnership Between DKFZ and University Medical Center Freiburg, Heidelberg, Germany.ORCID 0000-0001-6565-3393
Jan-Bernd HövenerSektion Biomedizinsche Bildgebung, Molecular Imaging North Competence Center MOINCC, Klinik Für Radiologie und Neuroradiologie, University Hospital Schleswig-Holstein, Kiel University, Kiel, Germany.
Thomas ReinheckelGerman Cancer Consortium (DKTK), Partner Site Freiburg, a Partnership Between DKFZ and University Medical Center Freiburg, Heidelberg, Germany.
Olaf GroßGerman Cancer Consortium (DKTK), Partner Site Freiburg, a Partnership Between DKFZ and University Medical Center Freiburg, Heidelberg, Germany.
Andreas B SchmidtDivision of Medical Physics, Department of Radiology, Medical Center and Faculty of Medicine, Freiburg, Germany.ORCID 0000-0001-8944-7463

Funding

Bundesministerium für Wissenschaft, Forschung und RaumfahrtDeutsche ForschungsgemeinschaftDeutschen Konsortium für Translationale KrebsforschungEuropäischen Fonds für regionale EntwicklungEuropean Research Council 101034170European Research Council 101094168Research Commission of the University Medical Center Freiburg
6 · The paper itself

Abstract

Hyperpolarized (HP)

Indexed as

HydrogenPyruvic AcidCarbon-13 Magnetic Resonance SpectroscopyCarbon IsotopesHeLa CellsHumansMagnetic Resonance SpectroscopyCarbon IsotopesHydrogenPyruvic Acidbioreactorcarbon‐13hyperpolarizationmetabolismparahydrogenpyruvateSABRE

Identifiers

PMID42429181
PMCPMC13480487

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.