Evidence map›Paper›PMID 42429842›Full record

ArticleMolecular biology reports2026

Exploring the apoptotic potential of Prunus spinosa Trigno extract in BRAF-mutated melanoma cells.

Alessia Di Pauli, Rosa Vona, Alice Di Netta, Camilla Cittadini, Marika Berardini, Stefania Meschini, Maria Condello

Abstract read
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In one paragraph

Article in Molecular biology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alessia Di PauliDepartment of Anatomy, Histology, Forensic-Medicine and Orthopedics, Section of Histology and Embryology, Sapienza University of Rome, Rome, 00161, Italy.
Rosa VonaNational Center for Gender-Specific Medicine, National Institute of Health, Rome, 00161, Italy.
Alice Di NettaNational Center for Drug Research and Evaluation, National Institute of Health, Rome, 00161, Italy.
Camilla CittadiniNational Center for Infection Diseases, National Institute of Health, Rome, 00161, Italy.
Marika BerardiniDepartment of Anatomy, Histology, Forensic-Medicine and Orthopedics, Section of Histology and Embryology, Sapienza University of Rome, Rome, 00161, Italy.
Stefania MeschiniNational Center for Drug Research and Evaluation, National Institute of Health, Rome, 00161, Italy.
Maria CondelloNational Center for Drug Research and Evaluation, National Institute of Health, Rome, 00161, Italy. maria.condello@iss.it.ORCID https://orcid.org/0000-0002-2802-9142

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMelanoma is one of the most aggressive forms of cancer in human due to its ability to invade tissues and metastasize. The aim of this work is to examine the effect of our patented compound Prunus spinosa Trigno + Nutraceutical Activator Complex (PsT + NAC METHODS AND

resultsThe data show that PsT + NAC

conclusionThese results demonstrate the efficacy of PsT + NAC

Indexed as

ApoptosisMelanomaPlant ExtractsProto-Oncogene Proteins B-rafPrunusCell Line, TumorCell MovementCell ProliferationCell SurvivalHumansMutationBRAF protein, humanPlant ExtractsProto-Oncogene Proteins B-rafApoptosisAutophagyDrug resistanceMelanomaPrunus spinosa

Identifiers

PMID42429842

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.