Evidence mapPaperPMID 42430046Full record

ArticleOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2026

Analysis of the Association Between Weight Status and Myopia in Children and Adolescents and Development of a Screening Model Based on Body Fat Percentage.

Deqiang Zhao, Xiaoxiao Chen, Aoyu Zhang, Xiang Pan, Chunmiao Wang, Jiaxin Chen, Haixia Hu, Yanfeng Zhang

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Article in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Deqiang ZhaoChina Institute of Sport Science, Beijing, China.
Xiaoxiao ChenSchool of Physical Education and Sports Rehabilitation, Jinzhou Medical University, Jinzhou, China.
Aoyu ZhangTianshi College of Tianjin, School of Medicine, Tianjin, China.
Xiang PanGraduate School of Health and Sports Science, Juntendo University, Inzai, Japan.
Chunmiao WangChina Institute of Sport Science, Beijing, China.
Jiaxin ChenChina Institute of Sport Science, Beijing, China.
Haixia HuAiyoudong Children and Youth Sports Health Research Institute, Weifang, China.
Yanfeng ZhangChina Institute of Sport Science, Beijing, China. zhangyanfeng0310@126.com.

Funding

Special Project on "Scientific and Technological Countermeasures for Positive Health and Population Aging" under the National Key Research and Development Program of China 2022YFC3600204Weifang Children and Adolescents Sports-Health Integration Innovation and Development Initiative B2422Weifang Integration of Sports and Health Innovation and Development Project B2311
6 · The paper itself

Abstract

purposeThis study examined the association between weight status and myopia in children and adolescents and compared the screening performance of body mass index (BMI) and body fat percentage.

methodsThis cross-sectional study included 8748 students aged 7-15 years. Height, weight and body fat percentage were measured, and myopia was assessed using non-cycloplegic autorefraction. The sample was randomly divided into training and validation sets. Logistic regression adjusted for sex, age, residence, physical activity and outdoor light exposure was used to examine the association between weight status and myopia. Mediation analysis treated physical activity as a categorical variable, with bootstrap resampling used to test indirect effects through BMI and body fat percentage. Receiver operating characteristic curves compared the screening performance of both indicators.

resultsOverweight or obesity was associated with myopia after full adjustment (odds ratio = 1.45, 95% confidence interval: 1.30-1.63). Categorical mediation analysis showed a direct protective association of higher physical activity with myopia, with no significant indirect effect through BMI or body fat percentage. In both training and validation sets, the area under the curve was 0.76 for BMI and 0.76 for body fat percentage. A body fat percentage threshold of 0.69 classified a high-risk group with higher myopia prevalence than the low-risk group (88.7% versus 52.1%).

conclusionOverweight or obesity is independently associated with myopia. BMI and body fat percentage provide comparable, low-cost tools for initial school-based risk stratification, while physical activity may protect against myopia independently of body composition.

Indexed as

Body fat percentageChildren and adolescentsMyopiaOverweight and obesityROC curveScreening model

Identifiers

PMID42430046

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.