In one paragraphArticle in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
13 authors.
Lei HuangDepartment of Biomedical Engineering, Center for the Investigation of Membrane Excitability Diseases, Washington University in St. Louis, MO 63130, USA.ORCID 0009-0008-1728-3509 Nitzan DausDepartment of Physiology and Pharmacology, Gray Faculty of Medical and Health Sciences and Sagol School of Neurosciences, Tel Aviv University, Tel Aviv 6997801, Israel.ORCID 0009-0005-0600-5878 Yuyin WangDepartment of Biomedical Engineering, Center for the Investigation of Membrane Excitability Diseases, Washington University in St. Louis, MO 63130, USA.
Guohui ZhangDepartment of Biomedical Engineering, Center for the Investigation of Membrane Excitability Diseases, Washington University in St. Louis, MO 63130, USA.ORCID 0000-0001-6905-0637 Manar KhierDepartment of Physiology and Pharmacology, Gray Faculty of Medical and Health Sciences and Sagol School of Neurosciences, Tel Aviv University, Tel Aviv 6997801, Israel.ORCID 0009-0005-3556-4986 Ariel Ben-BassatDepartment of Physiology and Pharmacology, Gray Faculty of Medical and Health Sciences and Sagol School of Neurosciences, Tel Aviv University, Tel Aviv 6997801, Israel.ORCID 0000-0002-7403-2633 Jingyi ShiDepartment of Biomedical Engineering, Center for the Investigation of Membrane Excitability Diseases, Washington University in St. Louis, MO 63130, USA.ORCID 0009-0003-6252-7262 Lu ZhaoDepartment of Biomedical Engineering, Center for the Investigation of Membrane Excitability Diseases, Washington University in St. Louis, MO 63130, USA.ORCID 0000-0003-3533-7693 Borui ZhangDepartment of Biomedical Engineering, Center for the Investigation of Membrane Excitability Diseases, Washington University in St. Louis, MO 63130, USA.
Lu HanDepartment of Biomedical Engineering, Center for the Investigation of Membrane Excitability Diseases, Washington University in St. Louis, MO 63130, USA.ORCID 0009-0009-8938-7726 Yoni HaitinDepartment of Physiology and Pharmacology, Gray Faculty of Medical and Health Sciences and Sagol School of Neurosciences, Tel Aviv University, Tel Aviv 6997801, Israel.ORCID 0000-0002-1648-6792 Bernard AttaliDepartment of Physiology and Pharmacology, Gray Faculty of Medical and Health Sciences and Sagol School of Neurosciences, Tel Aviv University, Tel Aviv 6997801, Israel.ORCID 0000-0003-1066-7047 Jianmin CuiDepartment of Biomedical Engineering, Center for the Investigation of Membrane Excitability Diseases, Washington University in St. Louis, MO 63130, USA.ORCID 0000-0002-9198-6332 Funding
A full spectrum rational approach to identify antiarrhythmic agents targeting IKs ChannelsR01HL166628 · NHLBI · STATE UNIVERSITY NEW YORK STONY BROOK · PI Jianmin Cui, RICHARD Z LIN · 2023 to 2026
$2.8MGating Mechanisms of KCNQ1/IKS ChannelsR01HL155398 · NHLBI · WASHINGTON UNIVERSITY · PI CUI, JIANMIN · 2021 to 2024
$2.5MNHLBI NIH HHS R01 HL155398NHLBI NIH HHS R01 HL166628
6 · The paper itselfAbstract
In classic models of voltage-dependent channel activation, the pore only opens after the voltage sensor domains (VSDs) activate in an "all-or-none" fashion. Whether the VSD alters open pore properties remains unclear. Here, we examine the properties of the KCNQ1 channel pore in relation with the VSD and regulatory subunits that are located outside of the pore using barium ion (Ba
Indexed as
BariumIon Channel GatingKCNQ1 Potassium ChannelPotassium Channels, Voltage-GatedAnimalsHumansProtein SubunitsBariumKCNQ1 Potassium ChannelPotassium Channels, Voltage-GatedProtein Subunits
Identifiers
PMID42430481
PMCPMC13353409
What Socratic holds
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