Evidence map›Paper›PMID 42432389›Full record

ArticleCardiovascular toxicology2026

Molecular Mechanisms of Effects of Lead and Cadmium Co-exposure on Atrial and Ventricular Myocardium: Soluble Salts Versus Nanoparticles.

Oksana Gerzen, Veronika Votinova, Salavat Nabiev, Alyona Tzybina, Natalia Stukalova, Maria Zhigulina, Svetlana Klinova, Ilzira Minigalieva, Marina Sutunkova, Larisa Nikitina

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Cardiovascular toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Oksana GerzenInstitute of Immunology and Physiology of Ural Branch of the Russian Academy of Sciences, 620049, Yekaterinburg, Russian Federation. o.p.gerzen@gmail.com.ORCID 0000-0003-3853-1571
Veronika VotinovaInstitute of Immunology and Physiology of Ural Branch of the Russian Academy of Sciences, 620049, Yekaterinburg, Russian Federation.ORCID 0009-0001-0647-0519
Salavat NabievInstitute of Immunology and Physiology of Ural Branch of the Russian Academy of Sciences, 620049, Yekaterinburg, Russian Federation.ORCID 0000-0001-9095-6775
Alyona TzybinaInstitute of Immunology and Physiology of Ural Branch of the Russian Academy of Sciences, 620049, Yekaterinburg, Russian Federation.ORCID 0009-0005-7362-2470
Natalia StukalovaInstitute of Immunology and Physiology of Ural Branch of the Russian Academy of Sciences, 620049, Yekaterinburg, Russian Federation.ORCID 0009-0001-0017-7573
Maria ZhigulinaInstitute of Immunology and Physiology of Ural Branch of the Russian Academy of Sciences, 620049, Yekaterinburg, Russian Federation.ORCID 0009-0003-6473-648X
Svetlana KlinovaYekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, 620014, Yekaterinburg, Russian Federation.ORCID 0000-0002-0927-4062
Ilzira MinigalievaYekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, 620014, Yekaterinburg, Russian Federation.ORCID 0000-0002-0097-7845
Marina SutunkovaYekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, 620014, Yekaterinburg, Russian Federation.ORCID 0000-0002-1743-7642
Larisa NikitinaInstitute of Immunology and Physiology of Ural Branch of the Russian Academy of Sciences, 620049, Yekaterinburg, Russian Federation.ORCID 0000-0002-7174-2357

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lead (Pb) and cadmium (Cd) are ubiquitous xenobiotics associated with cardiovascular diseases. While Pb and Cd cardiotoxicity is well studied, the molecular mechanisms of their co-exposure are poorly understood. We aimed to investigate the cardiotoxic effects of subchronic co-exposure to soluble versus nanoparticle forms of Pb and Cd on the atrial and ventricular myocardium. Rats received 18 intraperitoneal injections of combined Pb(C

Indexed as

Cadmium ChlorideHeart AtriaHeart DiseasesHeart VentriclesMyocardiumMyocytes, CardiacNanoparticlesAnimalsCadmium CompoundsCardiac MyosinsCardiotoxicityLeadMaleMyocardial ContractionMyosin Heavy ChainsMyosin Light ChainsCadmium ChlorideCadmium Compoundscadmium oxideCardiac MyosinsLeadlead oxideMyosin Heavy ChainsMyosin Light ChainsOxidesVentricular MyosinsCadmiumCardiotoxicityHeart chambersLeadMyosinNanoparticles

Identifiers

PMID42432389

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.