ArticleMedicine2026
Visual analysis of the literature on postmenopausal osteoporosis-related hormone research: Current status and future trends (2004-2024).
Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundPostmenopausal osteoporosis (PMOP) is a metabolic bone disease characterized by decreased bone mass and deteriorated bone microstructure. Despite advancements in hormone-related PMOP research, a systematic bibliometric analysis in this domain remains absent.
objectiveThis study employs bibliometric methods to delineate global trends, key contributors, and research hotspots in PMOP-related hormone studies (2004-2024), providing evidence-based guidance for future investigations. STUDY
designA comprehensive analysis was conducted using 2004 to 2024 literature systematically retrieved from the Web of Science Core Collection database, focusing on PMOP-hormone interactions.
methodsCiteSpace (6.3.R1) facilitated multidimensional analyses of countries, institutions, authors, journals, co-cited references, and keywords. Network optimization utilized g-index (k = 25) node filtering and the PathFinder algorithm for structural refinement.
resultsAmong 7174 analyzed publications, China and the United States dominated research output (46.94% combined). Leading institutions included the University of California System and Harvard University, with Osteoporosis International as the most active journal. Keyword clustering revealed emerging hotspots: oxidative stress (cluster #0), vitamin D deficiency, and romosozumab, demonstrating the centrality of estrogen receptor-related studies.
conclusionThis pioneering bibliometric study establishes a knowledge mapping framework for PMOP-hormone research, elucidating multidimensional associations between hormonal regulation and bone metabolism. Findings underscore oxidative stress-hormone axis modulation and romosozumab-targeted therapies as critical frontiers, while emphasizing the imperative for enhanced interdisciplinary collaboration to advance therapeutic innovation.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.