GuidelineJournal of evidence-based medicine2026
Guideline for Medication Management of Distressing Symptoms in Older Patients Receiving End-of-Life Palliative Care.
Guideline in Journal of evidence-based medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Older patients receiving end-of-life palliative care often present with multiple geriatric syndromes, frailty, and comorbid symptom burden, resulting in a high risk of medication-related harm. This guideline focuses on pharmacological management of distressing symptoms in older patients receiving end-of-life or hospice-oriented palliative care, rather than disease-modifying treatment of chronic conditions. The guideline was developed in accordance with the standards of the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) system and the Reporting Items for Practice Guidelines in Healthcare (RIGHT). It addresses 15 common distressing symptoms and provides 65 recommendations. On the basis of the best available evidence, patient values, feasibility, and expert consensus, the panel formulated recommendations intended to support safe, rational, individualized, and goal-concordant medication use in older patients at the end of life. This guideline aims to identify and recommend appropriate pharmacological treatments for common and refractory symptoms in older palliative care patients and to provide guidance for healthcare professionals on safe, rational, and standardized medication use.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.