ArticleEchocardiography (Mount Kisco, N.Y.)2026
Association of Echocardiographic Ventricular-Arterial Coupling With Elevated 10-Year ASCVD Risk in Hypertensive Patients.
Article in Echocardiography (Mount Kisco, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Association of Echocardiographic Ventricular-Arterial Coupling With Elevated 10-Year ASCVD Risk in Hypertensive Patients.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Moving the Goalposts in Hypertensive Risk Assessment: The AVI/LVGLS Ratio as a Sensitive Detector of Maladaptive Ventricular-Arterial Coupling.Echocardiography (Mount Kisco, N.Y.) · 2026Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
objectiveTo investigate the association between the arterial velocity pulse index-to-left ventricular global longitudinal strain ratio (AVI/LVGLS) and estimated 10-year atherosclerotic cardiovascular disease (ASCVD) risk assessed using the China-PAR model in patients with hypertension.
methodsA total of 190 patients with hypertension and 203 controls were included. Ventricular-arterial coupling (VAC) was assessed using the AVI/LVGLS ratio, with absolute LVGLS values used to ensure consistent directional interpretation. High estimated ASCVD risk was defined as ≥10%. Least absolute shrinkage and selection operator (LASSO) regression was used to identify potential predictors of elevated ASCVD risk. Multivariable logistic regression analyses were subsequently performed to evaluate the independent association between AVI/LVGLS and ASCVD risk using both continuous and categorical (lowest fifth percentile) approaches.
resultsAVI/LVGLS was significantly higher in patients with hypertension than in controls (p < 0.05). LASSO regression identified AVI/LVGLS as an important predictor of high estimated ASCVD risk. Receiver operating characteristic analysis demonstrated that AVI/LVGLS had superior discriminatory performance compared with VVI, AVI, and LVGLS alone. In multivariable logistic regression analysis, AVI/LVGLS below the fifth percentile was independently associated with high estimated ASCVD risk after adjustment for conventional cardiovascular risk factors (OR = 6.106, 95% CI: 1.352-27.565, p = 0.019).
conclusionVAC, assessed by AVI/LVGLS ratio, was independently associated with increased estimated ASCVD risk in patients with hypertension. AVI/LVGLS may reflect integrated myocardial and vascular alterations and could serve as a complementary marker for cardiovascular risk stratification in this population.
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Registered trials
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