Evidence map›Paper›PMID 42433630›Full record

ArticleEuropean heart journal open2026

Narrowing sex differences in pharmacotherapy following invasive angiography for coronary artery disease between 2017 and 2024.

Andrew J Sullivan, Zin Tun, Margaret Siu, Manisha Rai, Gloria Antoun, Nandini Rawat, Rebecca Walker, Alexandros Kythreotis, Abdelmajid Al Jariri, Asad Shabbir and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European heart journal open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Andrew J SullivanBarts and the London Faculty of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.ORCID https://orcid.org/0000-0001-8556-0530
Zin TunBarts Heart Centre, Barts Health NHS Trust, London, West Smithfield, London, EC1A 7BE, UK.
Margaret SiuBarts and the London Faculty of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Manisha RaiBarts and the London Faculty of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Gloria AntounBarts and the London Faculty of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Nandini RawatBarts and the London Faculty of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Rebecca WalkerBarts and the London Faculty of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Alexandros KythreotisBarts and the London Faculty of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Abdelmajid Al JaririBarts Heart Centre, Barts Health NHS Trust, London, West Smithfield, London, EC1A 7BE, UK.
Asad ShabbirBarts and the London Faculty of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Shane CashinBarts Heart Centre, Barts Health NHS Trust, London, West Smithfield, London, EC1A 7BE, UK.
Anthony MathurBarts and the London Faculty of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.ORCID https://orcid.org/0000-0001-7941-9653
Daniel A JonesBarts and the London Faculty of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Ajay GuptaBarts and the London Faculty of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Krishnaraj S RathodBarts and the London Faculty of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
Amrita AhluwaliaBarts and the London Faculty of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.ORCID https://orcid.org/0000-0001-7626-6399

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Women who experience myocardial infarction (MI) and undergo invasive angiography, experience higher morbidity and mortality compared to age-matched male counterparts. The prognostic benefit of optimal medical therapy (OMT) following MI is well established; however, treatment bias has been evidenced historically between the sexes. We explored sex differences in prescribing trends of OMT following invasive angiography for obstructive CAD at a high throughput regional cardiac centre. Methods: We determined discharge medication received by females and males undergoing invasive angiography in 2017, 2019, 2022, and 2024 with obstructive CAD (angiographic lesion ≥50% luminal diameter). Logistic regression was used to determine differences in the main cohort and in subgroups by clinical diagnosis (ACS, STEMI, NSTEMI, stable angina) and age (<55 or ≥55 years). This latter age cut-off to explore pre- and post-menopause trends, respectively. Results: 10 591 patient attendances (22.3% female, Conclusion: These findings demonstrate welcome improvements in equitable prescribing practices for OMT post angiography and highlight the importance of reviewing prescribing practices to ensure evidencing of success in implementing best practice guidelines.

Indexed as

Coronary artery diseaseMyocardial infarctionPharmacotherapySex characteristics

Identifiers

PMID42433630
PMCPMC13353530

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.