Evidence map›Paper›PMID 42433669›Full record

ArticleFrontiers in pediatrics2026

QTc interval prolongation in pediatric eating disorder population.

Emily Kacer, Erin Burnley, Terrel Marshall, Clarissa Ngo, Hon Yiu So, Allison Rodrigues, Narayanaswamy Balakrishnan, Tapas Mondal

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Emily KacerMichael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.
Erin BurnleyMichael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.
Terrel MarshallMichael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.
Clarissa NgoMichael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.
Hon Yiu SoDepartment of Mathematics and Statistics, Oakland University, Rochester, MI, United States.
Allison RodriguesDepartment of Pediatrics, Division of Adolescent Medicine, Health Sciences Centre, McMaster University, Hamilton, ON, Canada.
Narayanaswamy BalakrishnanDepartment of Mathematics and Statistics, McMaster University, Hamilton, ON, Canada.
Tapas MondalDepartment of Pediatrics, Division of Cardiology, Health Sciences Centre, McMaster University, Hamilton, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Eating disorders in pediatric populations are associated with several cardiac complications, including QTc prolongation, which can lead to fatal arrhythmias. While some studies suggest eating disorders inherently lead to QTc prolongation, emerging evidence suggests extrinsic factors may play a greater role. Methods: This retrospective chart review evaluates QTc interval prolongation in pediatric patients with eating disorders at a tertiary children's hospital. Demographic factors, ECGs, electrolyte levels, and the use of QTc-prolonging medications were analyzed to evaluate their association with QTc prolongation. Results: Among 435 patients, 405 had normal QTc intervals (<440 ms), 8 were borderline prolonged (440-460 ms), and 22 had prolonged intervals (>460 ms) using the Bazett calculation. Mean QTc values differed significantly across eating disorder subtypes ( Discussion: These findings suggest QTc-prolonging medications and electrolyte abnormalities can be associated with longer QTc intervals in pediatric patients with eating disorders and should continue to be monitored as modifiable risk factors.

Indexed as

eating disorderelectrolytesmedicationspediatricQTc interval

Identifiers

PMID42433669
PMCPMC13349899

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.