Evidence map›Paper›PMID 42433866›Full record

ArticleAnnals of medicine and surgery (2012)2026

Efficacy and safety of optical coherence tomography-guided versus angiography-guided percutaneous coronary intervention: a systematic review and meta-analysis.

Muhammad Raffey Shabbir, Allahdad Khan, Safiullah Soomro, Mujahid Ali, Maryam Tariq, Atika Shahzadi, Shafique Ahmed, Anees Ali Barkat, Muhammad Daniyal Basheer, Usha Kumari and 7 more

Abstract read
In one paragraph

Article in Annals of medicine and surgery (2012), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Muhammad Raffey ShabbirDepartment of Internal Medicine, Marshfield Clinic, Marshfield, WI, USA.
Allahdad KhanDepartment of Medicine, Nishtar Medical University, Multan, Pakistan.
Safiullah SoomroDepartment of Medicine, Dow University of Health Science, Karachi, Pakistan.
Mujahid AliDepartment of Medicine, Nishtar Medical University, Multan, Pakistan.
Maryam TariqDepartment of Medicine, Rawalpindi Medical University, Rawalpindi, Pakistan.
Atika ShahzadiDepartment of Medicine, Frontier Medical and Dental College, Abbottabad, Pakistan.
Shafique AhmedDepartment of Medicine, IUK ISM, Bishkek, Kyrgyzstan.
Anees Ali BarkatDepartment of Medicine, Allama Iqbal Medical College, Lahore, Pakistan.
Muhammad Daniyal BasheerDepartment of Medicine, Abbas Institute of Medical Sciences, Muzaffarabad, Pakistan.
Usha KumariDepartment of Medicine, Dow University of Health Science, Karachi, Pakistan.
Mohammad Ebad Ur RehmanDepartment of Medicine, Rawalpindi Medical University, Rawalpindi, Pakistan.
Huzaifa Ahmad CheemaDepartment of Medicine, King Edward Medical University, Lahore, Pakistan.
Asma'a Munasar Ali AlsubariDepartment of Medicine, Sana'a University, Sana'a, Yemen.ORCID https://orcid.org/0009-0005-1722-3926
Muhammad Aslam KhanDepartment of Internal Medicine, Guthrie Robert Packer Hospital, Sayre, PA, USA.
Bilawal NadeemDepartment of Internal Medicine, Boston Medical Center, Boston, MA, USA.
Raheel AhmedDepartment of Cardiovascular Medicine, National Heart & Lung Institute, Imperial College London, London, UK.
Adeel AhmadDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The optimal imaging guidance for percutaneous coronary intervention (PCI) in complex coronary lesions remains a matter of debate. This meta-analysis compares the efficacy and safety of optical coherence tomography (OCT)-guided PCI versus angiography-guided PCI. Methods: Following PRISMA guidelines, we systematically searched PubMed, Embase, Cochrane, and ClinicalTrials.gov from inception to December 2024. Randomized controlled trials (RCTs) comparing OCT-guided PCI to angiography-guided PCI were included. Data analysis was performed using RevMan 5.4, with risk ratios (RR) and 95% confidence intervals (CI) calculated for dichotomous outcomes using a random-effects model. Risk of bias was assessed using the Cochrane RoB 2.0 tool. Results: Eleven RCTs involving 6432 participants were included. OCT-guided PCI showed no statistically significant reduction in all-cause mortality compared to angiography-guided PCI (RR 0.72, 95% CI 0.51-1.01, Conclusion: OCT-guided PCI demonstrated significant benefits in reducing cardiac death, MACE, and procedural complications compared to angiography-guided PCI. These findings support the integration of OCT in complex PCI, although further studies are warranted to assess its impact on long-term mortality.

Indexed as

angiographyoptical coherence tomographypercutaneous coronary intervention

Identifiers

PMID42433866
PMCPMC13354332

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.