Evidence map›Paper›PMID 42434172›Full record

ArticleToxicology reports2026

Molecular dynamics and predictive toxicity insights into theaflavin as a potential inhibitor of MMP-2 and MMP-9 in breast cancer.

Iwan Benny Purwowidodo, Farid Sri Lingganingrum, Riska Prasetiawati, Nining Juliani, Taufik Muhammad Fakih, Dhania Novitasari, Ezatul Ezleen Kamarulzaman, Muchtaridi Muchtaridi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Iwan Benny PurwowidodoKonsep Karnus - PT. Alga Rosan Nusantara, Gading Fajar, Blok A1 No. 21, Buduran, Sidoarjo 61252, Indonesia.
Farid Sri LingganingrumKonsep Karnus - PT. Alga Rosan Nusantara, Gading Fajar, Blok A1 No. 21, Buduran, Sidoarjo 61252, Indonesia.
Riska PrasetiawatiDepartment of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Garut, Jl. Jati, Garut 44151, Indonesia.
Nining JulianiDepartment of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Garut, Jl. Jati, Garut 44151, Indonesia.
Taufik Muhammad FakihDepartment of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Islam Bandung, Jl. Ranggagading, Bandung 40116, Indonesia.
Dhania NovitasariDepartment of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Jl. Raya Bandung-Sumedang, Sumedang 45363, Indonesia.
Ezatul Ezleen KamarulzamanSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, USM Health Campus, 11800 Gelugor, Penang, Malaysia.
Muchtaridi MuchtaridiDepartment of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Jl. Raya Bandung-Sumedang, Sumedang 45363, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is one of the most commonly diagnosed malignancies in women and remains a leading cause of cancer-related mortality worldwide. Matrix metalloproteinases (MMPs), particularly Matrix Metalloproteinase-2 (MMP-2) and Matrix Metalloproteinase-9 (MMP-9), play critical roles in cancer invasion, metastasis, and angiogenesis, making them attractive therapeutic targets. Theaflavin, a major polyphenolic compound derived from black tea (

Indexed as

Black tea (Camellia sinensis)Breast cancerMatrix metalloproteinase−2 (MMP−2)Matrix metalloproteinase−9 (MMP−9)Molecular simualtions

Identifiers

PMID42434172
PMCPMC13351187

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.