ReviewJournal of clinical and experimental dentistry2026
Bioactivity and dimensional stability of resin-, hybrid-, and silicate-based endodontic sealers: An in vitro comparative study.
Review in Journal of clinical and experimental dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The success of endodontic treatment depends on selecting sealers with suitable physicochemical and biological properties. Solubility, pH, and calcium ion (Ca²+) release are critical factors influencing biocompatibility, antimicrobial activity, and long-term sealing. Material and Methods: This in vitro study compared three endodontic sealers, AH Plus (AHP), MTA Fillapex (MTAF), and EndoSequence BC Sealer (ESBC). pH was measured with a digital pH meter, and Ca²+ release was determined by atomic absorption spectrophotometry after 3, 24, 72, and 168 hours. Volumetric solubility was analyzed using micro-computed tomography before and after 7 days of immersion. Results: All sealers exhibited an alkaline pH. ESBC showed the highest pH and Ca²+ release at all time points, followed by MTAF. AHP released minimal and progressively decreasing calcium release. In volumetric analysis, ESBC demonstrated the greatest solubility, with pronounced volume reduction, whereas AHP and MTAF showed slight mass gain, indicating greater dimensional stability. Conclusions: Although ESBC exhibited higher bioactive potential, its excessive solubility may impair long-term sealing. AHP and MTAF presented more stable dimensional behavior, suggesting better long-term performance. These in vitro results highlight the balance between bioactivity and stability as a key factor when selecting root canal sealers for clinical use.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.