ArticleJournal of gastrointestinal oncology2026
Identification and preliminary examination of prognostic genes linked to calcium metabolism in colorectal cancer.
Article in Journal of gastrointestinal oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
Background: Colorectal cancer (CRC) is a substantial global health challenge due to high mortality rates. This study focused on constructing and validating a calcium metabolism-related genes (CAMRGs) signature for CRC outcome prediction. Methods: Transcriptomic and clinical data for CRC were integrated from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. A prognostic risk model was constructed using least absolute shrinkage and selection operator (LASSO)-Cox regression analysis. The predictive performance of the model was validated using an external dataset (GSE17536). Furthermore, the expression levels of the identified prognostic genes were preliminarily assessed via reverse transcription-quantitative polymerase chain reaction (RT-qPCR) in clinical specimens. Results: Conclusions: A CAMRG signature was developed and preliminary examination of CRC prognosis prediction. This model might assist in risk assessment and inform individualized treatment strategies.
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