Evidence map›Paper›PMID 42434337›Full record

ArticleBiochemistry and biophysics reports2026

Investigation of Epstein-Barr virus or human cytomegalovirus in pediatric gliomas: A retrospective single-center study from Tunisia.

Nabiha Missaoui, Ahlem Bdioui, Zaineb Lajmi, Syrine Moussa, Yosra Suiden, Nouha Jradi, Oussama Belkacem, Amal Bouazzi, Sarra Mestiri, Ksira Iadh and 1 more

Abstract read
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In one paragraph

Article in Biochemistry and biophysics reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nabiha MissaouiResearch Laboratory LR21ES03, Oncogenesis and Tumor Progression, Medicine Faculty of Sousse, University of Sousse, Sousse, 4002, Tunisia.
Ahlem BdiouiPathology Department, Sahloul University Hospital, Sousse, 4011, Tunisia.
Zaineb LajmiPathology Department, Sahloul University Hospital, Sousse, 4011, Tunisia.
Syrine MoussaPathology Department, Sahloul University Hospital, Sousse, 4011, Tunisia.
Yosra SuidenResearch Laboratory LR21ES03, Oncogenesis and Tumor Progression, Medicine Faculty of Sousse, University of Sousse, Sousse, 4002, Tunisia.
Nouha JradiResearch Laboratory LR21ES03, Oncogenesis and Tumor Progression, Medicine Faculty of Sousse, University of Sousse, Sousse, 4002, Tunisia.
Oussama BelkacemBiopathology Department, Institut Paoli-Calmettes, Marseille, 13009, France.
Amal BouazziDepartment of General Surgery, Sahloul University Hospital, Sousse, 4011, Tunisia.
Sarra MestiriPathology Department, Sahloul University Hospital, Sousse, 4011, Tunisia.
Ksira IadhNeurosurgery Department, Sahloul University Hospital, Sousse, 4011, Tunisia.
Sihem HmissaResearch Laboratory LR21ES03, Oncogenesis and Tumor Progression, Medicine Faculty of Sousse, University of Sousse, Sousse, 4002, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The involvement of infectious agents in glioma pathogenesis remains controversial. While adult gliomas have been extensively studied, the potential contribution of viral infections to pediatric gliomagenesis is poorly understood. This study aimed to assess the presence of two herpesviruses, Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV), in pediatric gliomas from Tunisian patients. A retrospective investigation of 30 archived pediatric glioma samples was conducted. EBV detection involves PCR targeting the BamM region, in situ hybridization (ISH) for EBER1/2 transcripts, and immunohistochemistry (IHC) for the LMP1 oncoprotein. HCMV was evaluated via PCR amplification of the

Indexed as

EBVGliomagenesisHCMVHerpesvirusPediatric gliomaTunisia

Identifiers

PMID42434337
PMCPMC13352032

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.