ArticleInternational journal of microbiology2026
Gut Microbiota Differences in Down Syndrome Are Most Pronounced in Childhood and Diminish With Age.
Article in International journal of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Gut Microbiota Differences in Down Syndrome Are Most Pronounced in Childhood and Diminish With Age.International journal of microbiology · 2026Article
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Authors and funding
11 authors.
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Abstract
Introduction: Down syndrome (DS) is linked to increased risks of metabolic, gastrointestinal, and neurodegenerative disorders. Early alterations in the gut microbiota have potential long-term health impacts. This report appears to be the first study to stratify DS participants by age to explore early-life microbiota changes. Methodology: We conducted a cross-sectional analysis of gut microbiota in children, adolescents, and adults with DS, compared with a control group, using Illumina iSeq100 sequencing of the V4 polymorphic region of the 16S rRNA gene. Results: Children with DS exhibited lower microbial diversity and a higher abundance of genera such as Conclusion: Early alterations in gut microbiota in DS may contribute to metabolic and neurodegenerative risks, emphasizing the need for early interventions to potentially improve long-term health outcomes.
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Registered trials
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