Evidence map›Paper›PMID 42434403›Full record

ArticleFrontiers in bioengineering and biotechnology2026

Bioprinted skin: from lab bench to clinic, what matters now and what's next.

Diala Haykal, Frédéric Flament, Pascale Mora, Bambou Tan, Caroline Sirichandra

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Diala HaykalCentre Laser Palaiseau, Private Practice, Palaiseau, France.
Frédéric FlamentL'Oreal Research and Innovation, Clichy, France.
Pascale MoraL'Oreal Research and Innovation, Clichy, France.
Bambou TanL'Oreal Research and Innovation, Clichy, France.
Caroline SirichandraEpiskin, Lyon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioprinted skin has emerged as a disruptive technology at the intersection of tissue engineering and plastic surgery. Through controlled deposition of bioinks containing living cells and biomaterials, it is now possible to create human skin constructs with unprecedented physiological fidelity. These constructs are already transforming the evaluation of drugs and cosmetics by providing reproducible, human-relevant alternatives to animal testing. In reconstructive and aesthetic surgery, bioprinted skin holds the promise of patient-specific grafts that integrate seamlessly, accelerate healing, and minimize scarring and pigmentation mismatch. This article explores the clinical, technical, and translational dimensions of bioprinted skin, with particular emphasis on fabrication strategies, bioink design, and current limitations. It further highlights the role of imaging, artificial intelligence, and advanced biomaterials in accelerating clinical translation while critically discussing the challenges that still prevent widespread implementation.

Indexed as

animal-free testingartificial intelligencebiofabricationbioprintingimaging innovationplastic surgeryregenerative medicinetissue engineering

Identifiers

PMID42434403
PMCPMC13350229

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.