Evidence map›Paper›PMID 42434514›Full record

ArticleaBIOTECH2026

AI-designed OpenCRISPR-1 enables efficient targeted mutagenesis and prime editing in rice.

Ajay Gupta, Rabia Ahuja, Bo Liu, Mark Adero, Dung Thi Pham, Wolf B Frommer, Bing Yang

Abstract read
In one paragraph

Article in aBIOTECH, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ajay GuptaDivision of Plant Science and Technology, Bond Life Sciences Center, University of Missouri, Columbia, MO, 65211, USA.
Rabia AhujaDivision of Plant Science and Technology, Bond Life Sciences Center, University of Missouri, Columbia, MO, 65211, USA.
Bo LiuDivision of Plant Science and Technology, Bond Life Sciences Center, University of Missouri, Columbia, MO, 65211, USA.
Mark AderoDivision of Plant Science and Technology, Bond Life Sciences Center, University of Missouri, Columbia, MO, 65211, USA.
Dung Thi PhamDivision of Plant Science and Technology, Bond Life Sciences Center, University of Missouri, Columbia, MO, 65211, USA.
Wolf B FrommerHeinrich Heine University Düsseldorf, Faculty of Mathematics and Natural Sciences, Institute for Molecular Physiology, Düsseldorf, 40225, Germany.
Bing YangDivision of Plant Science and Technology, Bond Life Sciences Center, University of Missouri, Columbia, MO, 65211, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in generative artificial intelligence (AI) have enabled the

Indexed as

AI designed OpenCRISPR-1Bacterial blightCRISPR-Cas9Freedom to operate (FTO)Open sourcePrime editingRice (Oryza sativa)

Identifiers

PMID42434514
PMCPMC13352068

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.