Evidence map›Paper›PMID 42434525›Full record

ArticleRegenerative biomaterials2026

Dual-functional micro- to nano-CFR-PEEK: promoting Hippo-mediated osseointegration while inhibiting

Yuxuan Lin, Huilian Zhang, Shiqiang Wang, Ge Yin, Yongmin Wu, Xinze Weng, Lixia Lin, Yan Chen, Yingzhen Lai, Jingjing Su

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Regenerative biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuxuan LinStomatological Hospital of Xiamen Medical College; School of Stomatology of Xiamen Medical College; Xiamen Key Laboratory of Stomatological Disease Diagnosis and Treatment; Engineering Research Center of Stomatological Biomaterials, Fujian Province University, Xiamen Medical College, Xiamen 361000, China.ORCID https://orcid.org/0009-0003-4982-115X
Huilian ZhangStomatological Hospital of Xiamen Medical College; School of Stomatology of Xiamen Medical College; Xiamen Key Laboratory of Stomatological Disease Diagnosis and Treatment; Engineering Research Center of Stomatological Biomaterials, Fujian Province University, Xiamen Medical College, Xiamen 361000, China.
Shiqiang WangStomatological Hospital of Xiamen Medical College; School of Stomatology of Xiamen Medical College; Xiamen Key Laboratory of Stomatological Disease Diagnosis and Treatment; Engineering Research Center of Stomatological Biomaterials, Fujian Province University, Xiamen Medical College, Xiamen 361000, China.
Ge YinStomatological Hospital of Xiamen Medical College; School of Stomatology of Xiamen Medical College; Xiamen Key Laboratory of Stomatological Disease Diagnosis and Treatment; Engineering Research Center of Stomatological Biomaterials, Fujian Province University, Xiamen Medical College, Xiamen 361000, China.
Yongmin WuStomatological Hospital of Xiamen Medical College; School of Stomatology of Xiamen Medical College; Xiamen Key Laboratory of Stomatological Disease Diagnosis and Treatment; Engineering Research Center of Stomatological Biomaterials, Fujian Province University, Xiamen Medical College, Xiamen 361000, China.
Xinze WengStomatological Hospital of Xiamen Medical College; School of Stomatology of Xiamen Medical College; Xiamen Key Laboratory of Stomatological Disease Diagnosis and Treatment; Engineering Research Center of Stomatological Biomaterials, Fujian Province University, Xiamen Medical College, Xiamen 361000, China.
Lixia LinStomatological Hospital of Xiamen Medical College; School of Stomatology of Xiamen Medical College; Xiamen Key Laboratory of Stomatological Disease Diagnosis and Treatment; Engineering Research Center of Stomatological Biomaterials, Fujian Province University, Xiamen Medical College, Xiamen 361000, China.
Yan ChenStomatological Hospital of Xiamen Medical College; School of Stomatology of Xiamen Medical College; Xiamen Key Laboratory of Stomatological Disease Diagnosis and Treatment; Engineering Research Center of Stomatological Biomaterials, Fujian Province University, Xiamen Medical College, Xiamen 361000, China.
Yingzhen LaiStomatological Hospital of Xiamen Medical College; School of Stomatology of Xiamen Medical College; Xiamen Key Laboratory of Stomatological Disease Diagnosis and Treatment; Engineering Research Center of Stomatological Biomaterials, Fujian Province University, Xiamen Medical College, Xiamen 361000, China.
Jingjing SuStomatological Hospital of Xiamen Medical College; School of Stomatology of Xiamen Medical College; Xiamen Key Laboratory of Stomatological Disease Diagnosis and Treatment; Engineering Research Center of Stomatological Biomaterials, Fujian Province University, Xiamen Medical College, Xiamen 361000, China.ORCID https://orcid.org/0000-0003-1360-3735

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To construct a biomimetic hierarchical topography on carbon fiber-reinforced polyetheretherketone (CFR-PEEK) to enhance multifaceted biological performance, CFR-PEEK substrates were modified via a one-step nitration-sulfonation treatment using mixed nitric and sulfuric acids at various volume ratios. The resulting surface topographies were systematically evaluated for

Indexed as

angiogenesisantibacterialcarbon fiber-reinforced polyetheretherketoneHippo-YAP/TAZmicro-to-nano hierarchical topographyosseointegrationosteoclast inhibitionsulfonation-nitration

Identifiers

PMID42434525
PMCPMC13350894

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.