Evidence map›Paper›PMID 42434564›Full record

ArticleFrontiers in microbiology2026

HtPIP: High-throughput phage isolation platform increases diversity and reduces isolation time using multiple bacteria.

Ben Diaz, Tessa House, Meghana Padala, Joseph S Schoeniger, Catherine M Mageeney

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ben DiazDepartment of Bioengineering and Biotechnology, Sandia National Laboratories, Livermore, CA, United States.
Tessa HouseDepartment of Bioengineering and Biotechnology, Sandia National Laboratories, Livermore, CA, United States.
Meghana PadalaDepartment of Bioengineering and Biotechnology, Sandia National Laboratories, Livermore, CA, United States.
Joseph S SchoenigerBiological, Radiation, and Signature Science, Technology, and Engineering Center, Sandia National Laboratories, Livermore, CA, United States.
Catherine M MageeneyDepartment of Bioengineering and Biotechnology, Sandia National Laboratories, Livermore, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteriophages are ubiquitous in nature, but relatively few have been isolated and characterized compared to the number of bacterial strains. Phage biotechnology applications benefit from a diverse library of isolated phages to kill or transfer genetic material to a bacterium of interest. However, scaling up phage discovery for diverse bacterial hosts can be time-consuming and costly. We developed an approach to capture novel phages for multiple bacterial strains in parallel from an environmental sample using commercially available 0.2-μM filter plates. Using this High-throughput Phage Isolation Platform (HtPIP), 12 novel phages were isolated spanning 9 diverse bacterial host genera. Eleven of the isolated phages define new phage species, with nine also defining new genera. The HtPIP was used to discover both DNA and RNA phages, including a

Indexed as

high-throughputphage discoveryphage diversityphage genomephages

Identifiers

PMID42434564
PMCPMC13351103

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.