Evidence map›Paper›PMID 42436452›Full record

ArticleBMC surgery2026

Risk factors for postoperative ecchymosis after medial open-wedge high tibial osteotomy: an exploratory analysis of thromboelastography parameters.

Yu Jiang, Jingyuan Li, Huan Liang, Liang Zhang, Wenlian Song, Tianrui Wang, Xia Zhao, Ning Yu, Yingze Zhang, Jinli Chen and 1 more

Abstract read
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Article in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Yu JiangKnee Preservation Centre, the Affiliated Hospital of Qingdao University, Qingdao, Shandong , 266000, China.
Jingyuan LiDepartment of Endocrine, Xiamen University Affiliated Xiang'an Hospital, Xiamen, Fujian, 361100, China.
Huan LiangManagement School, Ocean University of China, Qingdao, 266100, China.
Liang ZhangDepartment of Abdominal Ultrasound, Affiliated Hospital of Qingdao University, Qingdao, Shandong, 266000, China.
Wenlian SongJoint Surgery, Qingdao Municipal Hospital, Qingdao, 266000, China.
Tianrui WangKnee Preservation Centre, the Affiliated Hospital of Qingdao University, Qingdao, Shandong , 266000, China.
Xia ZhaoDepartment of Sports Medicine, the Affiliated Hospital of Qingdao University, Qingdao, Shandong, 266000, China.
Ning YuDepartment of Abdominal Ultrasound, Affiliated Hospital of Qingdao University, Qingdao, Shandong, 266000, China.
Yingze ZhangKnee Preservation Centre, the Affiliated Hospital of Qingdao University, Qingdao, Shandong , 266000, China.
Jinli ChenKnee Preservation Centre, the Affiliated Hospital of Qingdao University, Qingdao, Shandong , 266000, China. chenjinli2000@163.com.
Kuishuai XuKnee Preservation Centre, the Affiliated Hospital of Qingdao University, Qingdao, Shandong , 266000, China. 18661805466@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to identify risk factors for ecchymosis and its associated coagulation characteristics following medial open-wedge high tibial osteotomy (OWHTO) using thromboelastography (TEG).

methodsThis single-center retrospective study included 220 consecutive patients undergoing unilateral medial OWHTO between January 2023 and September 2025. All patients received rivaroxaban 10 mg orally once daily for 14 days, commencing 12 h postoperatively. The primary endpoint was the incidence of peri-incisional ecchymosis, assessed daily during the hospital stay (postoperative days 1-4). Patients were categorized into ecchymosis (n = 74) and no-ecchymosis groups. Pre-operative and post-operative day-4 TEG parameters, blood loss volumes, and baseline characteristics were analyzed. Multivariable logistic regression (variables selected based on clinical relevance and univariate P < 0.10) determined independent factors, while group discrimination was assessed descriptively using AUC.

resultsEcchymosis occurred in 33.6% (74/220) of patients. The ecchymosis group demonstrated higher BMI (mean difference 1.57 kg/m

conclusionsThis exploratory single-center retrospective analysis identified BMI, tourniquet time, and impaired perioperative recovery of the coagulation index as independently associated with ecchymosis following medial OWHTO. These findings detail a post-event coagulation status in patients developing ecchymosis under consistent perioperative anticoagulation; however, they do not support temporal or predictive inferences and remain hypothesis-generating. Prospective multicenter validation is necessary before any clinical utility can be inferred.

Indexed as

EcchymosisOsteotomyPostoperative ComplicationsThrombelastographyTibiaAdultAgedFactor Xa InhibitorsFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsRivaroxabanFactor Xa InhibitorsRivaroxabanAssociated factorsCoagulation functionEcchymosisOpen-wedge high tibial osteotomyThromboelastography

Identifiers

PMID42436452
PMCPMC13617702

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.