Evidence map›Paper›PMID 42436844›Full record

ReviewAnimal nutrition (Zhongguo xu mu shou yi xue hui)2026

Porcine intestinal goblet cells: Guardians of mucosal immunity and barrier function.

Chenbin Cui, Jiaxi Tang, Jing Hou, Jianjian Zhang, Min Tian, Kaiguo Gao, Li Wang, Zongyong Jiang, Xuefen Yang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chenbin CuiState Key Laboratory of Swine and Poultry Breeding, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, Guangdong, China.
Jiaxi TangState Key Laboratory of Swine and Poultry Breeding, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, Guangdong, China.
Jing HouState Key Laboratory of Swine and Poultry Breeding, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, Guangdong, China.
Jianjian ZhangState Key Laboratory of Swine and Poultry Breeding, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, Guangdong, China.
Min TianState Key Laboratory of Swine and Poultry Breeding, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, Guangdong, China.
Kaiguo GaoState Key Laboratory of Swine and Poultry Breeding, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, Guangdong, China.
Li WangState Key Laboratory of Swine and Poultry Breeding, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, Guangdong, China.
Zongyong JiangState Key Laboratory of Swine and Poultry Breeding, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, Guangdong, China.
Xuefen YangState Key Laboratory of Swine and Poultry Breeding, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Goblet cells are a type of secretory cell in the intestinal epithelium, characterized by their continuous production and secretion of mucin. Goblet cell-associated antigen passage (GAP)-mediated antigen presentation offers intestinal tolerance to innocuous luminal antigens and systemic resistance to infection. However, multiple factors can impair goblet cell abundance influencing mucin production in swine. Therefore, strategies aimed at maintaining porcine goblet cell homeostasis could provide an important role in the protection of gut health, ultimately enhancing porcine health and production performance. This review summarizes the current knowledge on porcine goblet cells, including methods of examination, their development and functions, and demonstrations of the presence of GAPs in the porcine small intestine. This review also lists the factors and nutrients that influence goblet cell homeostasis in swine production and discusses the potential roles of porcine goblet cells in nutrient digestion and absorption. Overall, this review highlights the importance of preserving the goblet cell-mediated portion of intestinal homeostasis and advances the understanding of porcine goblet cells, providing opportunities for the development of new methods to improve gut health in swine production.

Indexed as

Goblet cellGoblet cell-associated antigen passageGoblet cell developmentMucinNutrientPig

Identifiers

PMID42436844
PMCPMC13355209

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.