ArticleMolecular therapy. Advances2026
AAV-norrin gene therapy rescues retinal defects in mice with Norrie disease and oxygen-induced retinopathy.
Article in Molecular therapy. Advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Norrin, secreted by retinal Müller cells, activates canonical Wnt signaling via Frizzled-4 and co-receptors. Loss-of-function mutations abolish intraretinal capillary formation in mice. In humans, mutations in
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