Evidence map›Paper›PMID 42438377›Full record

SynthesisInternational wound journal2026

The Use of Adipose Derived Stem Cells in Chronic Wound Healing.

Siôna M Ladley, Seyran Naghdi

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in International wound journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Siôna M LadleyWarwick Medical School, University of Warwick, Coventry, UK.ORCID https://orcid.org/0009-0005-0134-3296
Seyran NaghdiWarwick Clinical Trials Unit, Warwick Medical School, Coventry, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound healing is a complex process of angiogenesis, inflammation and proliferation relying on co-ordination of multiple cell types and cytokines. Dysregulation of this process can lead to chronicity, which we are seeing more commonly due to an increasingly comorbid population. Adipose-Derived Stem Cells (ADSCs) show promise as a therapy though their ability to augment the tissue microenvironment via multiple pathways. This review aims to synthesise evidence on the effects of ADSCs on chronic wound healing to assess their efficacy. A systematic search of four databases was conducted covering a period up to June 2025. Comparative studies investigating ADSCs and wounds of any aetiology were included, and a meta-analysis was performed on pooled data. Ten studies were included in the meta-analysis (N = 498). Patients treated with ADSCs were more likely to heal at short-term follow-up (odds ratio (OR) 6.54, 95% confidence interval (CI) 3.80-11.27; n = 377 I

Indexed as

Adipose TissueStem CellsStem Cell TransplantationWound HealingWounds and InjuriesAdultAgedChronic DiseaseFemaleHumansMaleMiddle Agedadipose derived stem cellschronic woundsulcerswound healing

Identifiers

PMID42438377
PMCPMC13358368

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.