ArticleInternational journal of nanomedicine2026
Hafnium-Oxide Based Nanoplatform with Tumor Microenvironment Responsive Drug Release for Enhanced Radio-Chemotherapy.
Article in International journal of nanomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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12 authors.
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Abstract
Purpose: Hafnium oxide nanoparticles have been established as effective radiosensitizers, however, tumor cells often develop resistance to single-modality radiotherapy, and the tumor microenvironment (TME) poses additional limitations to treatment efficacy. To address these challenges, we fabricated a doxorubicin and manganese oxide co-loaded hafnium oxide (MD-Hf) nanoplatform for synergistic radio-chemotherapy and evaluated its antitumor performance in cellular and animal models. Results: In MD-Hf nanoplatform, the HfO Conclusion: The newly developed doxorubicin and manganese oxide co-loaded HfO
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